Evidence map›Paper›PMID 37830350›Full record

ArticleJournal of agricultural and food chemistry2023

Fermented Goat's Milk Contributes to the Recovery of Iron Deficiency Anemia via Modulation of the Gut Microbiome.

Ana Soriano-Lerma, María García-Burgos, María José M Alférez, Jorge Valentín Crespo-Pérez, Virginia Pérez-Carrasco, Matilde Ortiz-Gonzalez, Ángel Linde-Rodriguez, Victoria Sanchez-Martin, Miguel Soriano, Jose A Garcia-Salcedo and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Ana Soriano-LermaDepartment of Physiology (Faculty of Pharmacy, Campus Universitario de Cartuja), Institute of Nutrition and Food Technology "José Mataix Verdú", University of Granada, E-18071 Granada, Spain.ORCID 0000-0003-2830-1457
María García-BurgosDepartment of Physiology (Faculty of Pharmacy, Campus Universitario de Cartuja), Institute of Nutrition and Food Technology "José Mataix Verdú", University of Granada, E-18071 Granada, Spain.
María José M AlférezDepartment of Physiology (Faculty of Pharmacy, Campus Universitario de Cartuja), Institute of Nutrition and Food Technology "José Mataix Verdú", University of Granada, E-18071 Granada, Spain.ORCID 0000-0003-1598-7728
Jorge Valentín Crespo-PérezService of Anatomical Pathology, Intercenter Regional Unit Granada, University Hospital Virgen de las Nieves, E-18014 Granada, Spain.
Virginia Pérez-CarrascoGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, E-18016 Granada, Spain.
Matilde Ortiz-GonzalezGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, E-18016 Granada, Spain.ORCID 0000-0001-9977-5735
Ángel Linde-RodriguezGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, E-18016 Granada, Spain.ORCID 0000-0001-5954-8562
Victoria Sanchez-MartinGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, E-18016 Granada, Spain.ORCID 0000-0001-6870-3659
Miguel SorianoCenter for Intensive Mediterranean Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, E-04120 Almería, Spain.ORCID 0000-0002-1838-3615
Jose A Garcia-SalcedoGENYO, Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, E-18016 Granada, Spain.ORCID 0000-0003-3399-1835
Inmaculada López-AliagaDepartment of Physiology (Faculty of Pharmacy, Campus Universitario de Cartuja), Institute of Nutrition and Food Technology "José Mataix Verdú", University of Granada, E-18071 Granada, Spain.ORCID 0000-0001-7627-8760
Instituto de Investigación Biosanitaria de Granada · ESUniversidad de Granada · ESHospital Universitario Virgen de las Nieves · ESPfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ESUniversity of Almería · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anemia (IDA) is a global public health concern affecting 1.6 billion people worldwide. The administration of iron supplements during the treatment of IDA adversely affects the intestinal barrier function and the composition and functionality of the intestinal microbiome, both of which are already altered during IDA. For this reason, it is of great interest to develop nutritional strategies aimed at alleviating these gut alterations associated with IDA and its treatment. In this sense, fermented goat's milk (FGM) was studied due to its nutritional quality. Our findings showed that in anemic animals the consumption of a FGM-based diet, compared to a standard diet, had positive modulatory effects on the intestinal microbiome. FGM-based diet restored intestinal dysbiosis, the intestinal barrier functionality, and bacterial translocation, contributing to a more efficient recovery of IDA. Therefore, FGM is a useful nutritional tool to ease intestinal alterations occurring during IDA and during its treatment.

Indexed as

Anemia, Iron-DeficiencyGastrointestinal MicrobiomeAnimalsGoatsHumansIronMilkIronfermented goat’s milkfunctional foodsgoat’s milkgut microbiomeintestinal barrieriron deficiency anemianutrition

Identifiers

PMID37830350
PMCPMC11006235
OpenAlexW4387600057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.