Trial reportJournal of the American Heart Association2023
Randomized Controlled Trial of Moderate- and High-Intensity Exercise Training in Patients With Hypertrophic Cardiomyopathy: Effects on Fitness and Cardiovascular Response to Exercise.
Trial report in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Exercise Training in Hypertrophic Cardiomyopathy: A Systematic Review, Meta-analysis, and Meta-regression.Sports medicine - open · 2026Pooled it
- Efficacy and safety of exercise for hypertrophic cardiomyopathy: a systematic review and meta-analysis.Proceedings (Baylor University. Medical Center) · 2026Pooled it
- High intensity exercise programme in patients with hypertrophic cardiomyopathy: a randomized trial.European heart journal · 2025Trial
- Shared Decision Making on Methylphenidate in Hypertrophic Cardiomyopathy and ADHD in a Young Athlete.JACC. Case reports · 2026Article
- Unplanned Readmissions in Pediatric Cardiac Disease: Impacts of Social Determinants of Health.Pediatric cardiology · 2026Article
- Feasibility of an Individualized Exercise Training Program for Children with Hypertrophic Cardiomyopathy.Pediatric cardiology · 2026Article
- Exercise and Sport Participation in Pediatric Hypertrophic Cardiomyopathy: A Changing Paradigm.Current treatment options in cardiovascular medicine · 2026Review
- Exercise Participation and Rehabilitation in Cardiomyopathies: An Updated Review.Journal of clinical medicine · 2025Review
- Exercise Rehabilitation for Heart Failure and Associated Cardiomyopathies.Current cardiology reports · 2025Review
- Fit Hearts, Better Outcomes? A Systematic Review and Meta-Analysis of Exercise Intensity and Peak VOJournal of clinical medicine · 2025Review
- High-Intensity Training on Patients with Hypertrophic Cardiomyopathy: A Systematic Review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- The design and rationale of the cardiac REHABilitation to improve metabolic health in Hypertrophic CardioMyopathy (REHAB-HCM) Study.American heart journal plus : cardiology research and practice · 2025Article
- Comparative effects of moderate and high-intensity training on immune activation in myocarditis: a review of preclinical and clinical evidence.Frontiers in pharmacology · 2025Review
- "The Rule of 7": A Case of an Ambitious Master Duatlonist Who Experienced a Sudden Cardiac Arrest.Clinical Medicine Insights. Cardiology · 2025Article
- Exercise Alleviates Cardiovascular Diseases by Improving Mitochondrial Homeostasis.Journal of the American Heart Association · 2024Review
- Austrian consensus statement on the diagnosis and management of hypertrophic cardiomyopathy.Wiener klinische Wochenschrift · 2024Article
- Concurrent Resistance and Cardiorespiratory Training in Patients with Hypertrophic Cardiomyopathy: A Pilot Study.Journal of clinical medicine · 2024Article
- Mexican guidelines 2024 for the diagnosis and treatment of hypertrophic cardiomyopathy.Archivos de cardiologia de Mexico · 2024Article
- Contemporary review on pediatric hypertrophic cardiomyopathy: insights into detection and management.Frontiers in cardiovascular medicine · 2023Review
- Exercise across the cardiovascular continuum: expanding perspectives on its key role in contemporary clinical practice.Porto biomedical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Background Moderate intensity exercise training (MIT) is safe and effective for patients with hypertrophic cardiomyopathy, yet the efficacy of high intensity training (HIT) remains unknown. This study aimed to compare the efficacy of HIT compared with MIT in patients with hypertrophic cardiomyopathy. Methods and Results Patients with hypertrophic cardiomyopathy were randomized to either 5 months of MIT, or 1 month of MIT followed by 4 months of progressive HIT. Peak oxygen uptake (V˙O
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.