Evidence map›Paper›PMID 37830229›Full record

ArticleJournal of microbiology and biotechnology2024

Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway.

Yujin Kim, Jung Ok Lee, Jung Min Lee, Mun-Hoe Lee, Hyeong-Min Kim, Hee-Chul Chung, Do-Un Kim, Jin-Hee Lee, Beom Joon Kim

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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  6. A scATAC-seq atlas of stasis zone in rat skin burn injury wound process.Frontiers in cell and developmental biology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yujin KimDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Jung Ok LeeDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Jung Min LeeDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Mun-Hoe LeeHealth Food Research and Development, NEWTREE Co., Ltd., Seoul 05604, Republic of Korea.
Hyeong-Min KimHealth Food Research and Development, NEWTREE Co., Ltd., Seoul 05604, Republic of Korea.
Hee-Chul ChungHealth Food Research and Development, NEWTREE Co., Ltd., Seoul 05604, Republic of Korea.
Do-Un KimHealth Food Research and Development, NEWTREE Co., Ltd., Seoul 05604, Republic of Korea.
Jin-Hee LeeHealth Food Research and Development, NEWTREE Co., Ltd., Seoul 05604, Republic of Korea.
Beom Joon KimDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.
Wolters Kluwer Health · USChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low molecular weight collagen peptide (LMWCP) is a collagen hydrolysate derived from fish. We investigated the effects of LMWCP on hair growth using human dermal papilla cells (hDPCs), human hair follicles (hHFs), patch assay, and telogenic C57BL/6 mice, while also examining the underlying mechanisms of its action. LMWCP promoted proliferation and mitochondrial potential, and the secretion of hair growth-related factors, such as EGF, HB-EGF, FGF-4, and FGF-6 in hDPCs. Patch assay showed that LMWCP increased the neogeneration of new HFs in a dose-dependent manner. This result correlated with an increase in the expression of dermal papilla (DP) signature genes such as,

Indexed as

beta CateninWnt Signaling PathwayAnimalsCell ProliferationCells, CulturedGlycogen Synthase Kinase 3 betaHairHair FollicleHumansMiceMice, Inbred C57BLMolecular WeightVascular Endothelial Growth Factor Abeta CateninGlycogen Synthase Kinase 3 betaVascular Endothelial Growth Factor Ahuman dermal papilla cells (hDPCs)LMWCP (low molecular weight collagen peptide)VEGFWnt3aβ-catenin

Identifiers

PMID37830229
PMCPMC10840484
OpenAlexW4387597427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.