Evidence map›Paper›PMID 37830135›Full record

ArticleAnnals of clinical and translational neurology2023

Ischemic patterns and their angiographic risk factors in adult patients with moyamoya disease.

Si Luo, Wenjie Zhan, Lanjiao Zhang, Chenying Zeng, Daojun Hong, Pu Fang, Qianxi Chen, Jing Lin

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Si Luo *Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.ORCID 0009-0005-7868-9295
Wenjie Zhan *Department of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Lanjiao ZhangDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Chenying ZengDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Daojun HongDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.ORCID 0000-0003-1380-3534
Pu FangDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Qianxi ChenDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.
Jing LinDepartment of Neurology, The First Affiliated Hospital of Nanchang University, Nanchang, 330000, Jiangxi, China.ORCID 0000-0001-6272-1039
Nanchang University · CN

Funding

National Natural Science Foundation of China 82101405Natural Science Foundation of Jiangxi Province 20212BAB216023
6 · The paper itself

Abstract

objectiveThe present study aims to determine whether angiographic differences increase the risk of ischemic pattern among adult patients with moyamoya disease (MMD).

methodsFrom January 2020 to December 2021, we retrospectively enrolled 123 ischemic or asymptomatic adult patients diagnosed as MMD. Angiographic changes including Suzuki stage, moyamoya vessels, anterior choroidal artery (AChoA) dilatation, lenticulostriate artery (LSA) dilatation, posterior communicating artery (PcomA) dilatation, and posterior cerebral artery (PCA) involvement were evaluated for all patients.

resultsAmong the 123 participants, 35 ischemic patients and 88 asymptomatic patients were analyzed. There was no significant difference of Suzuki stage, AChoA dilatation, LSA dilatation, and PcomA dilatation between ischemic group and asymptomatic group. The grading of moyamoya vessels differed significantly but was not a factor associated with ischemic pattern after adjusting multiple related confounders. However, the frequency of PCA steno-occlusive changes in ischemic patients was statistically higher than that in asymptomatic patients (54.3% vs 34.1%, p = 0.039). Furthermore, PCA involvement was a risk factor associated with ischemic form and remained statistically significant after the multivariate adjustment (p = 0.033, 95% CI 1.092-8.310).

interpretationPCA involvement is closely related to the presentation of ischemic stroke but other angiographic features had no association with ischemic pattern in adult MMD.

Indexed as

Moyamoya DiseaseAdultCerebral AngiographyHumansIntracranial HemorrhagesRetrospective StudiesRisk Factors

Identifiers

PMID37830135
PMCPMC10723237
OpenAlexW4387599309

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.