Evidence map›Paper›PMID 37829956›Full record

ArticleCureus2023

An Adult With Undifferentiated Embryonal Sarcoma of the Liver: A Case Report of a Rare Encounter.

Rajmohan Rammohan, Melvin Joy, Sai Greeshma Magam, Achal Patel, Sai Reshma Magam, Dilman Natt, Jiten Desai, Susan Bunting, Paul Mustacchia

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rajmohan RammohanGastroenterology, Nassau University Medical Center, East Meadow, USA.
Melvin JoyInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Sai Greeshma MagamInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Achal PatelInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Sai Reshma MagamInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Dilman NattInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Jiten DesaiInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Susan BuntingInternal Medicine, Nassau University Medical Center, East Meadow, USA.
Paul MustacchiaGastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.
Nassau University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undifferentiated embryonal sarcoma of the liver (UESL) is a rare, aggressive tumor mainly found in children but can also appear in adults. Its diagnosis in adults remains a conundrum; it is often identified late due to its non-specific symptoms and resemblance to benign lesions. A comprehensive treatment regimen involving surgical intervention, chemotherapy, and possibly radiation significantly boosts survival rates. Imaging often yields inconclusive outcomes, further complicating the diagnostic process. Here, we report the case of a 28-year-old female diagnosed with UESL, emphasizing the need for timely intervention. Undifferentiated embryonal sarcoma of the liver requires differentiation from a variety of hepatic tumors in adults. Though there are no distinctive characteristics to differentiate UESL from other hepatic masses, its morphology and immunohistochemical profiles significantly vary. The staging often reveals UESL as a large, well-defined mass with the potential for diverse differentiation. Its prognosis has been considerably improved with the advent of multidisciplinary treatment. Surgical resection remains a cornerstone, often combined with chemotherapy. While pediatric cases exhibit better overall survival rates than adults, outcomes heavily depend on the chosen treatment regimen. A combination of chemotherapy and complete tumor removal has been found to significantly elevate survival chances. Disease recurrence remains a challenge and is influenced by treatment strategy. In conclusion, the diagnosis and treatment of UESL are fraught with challenges, particularly in adults. A multidimensional approach, combining various therapies, is paramount for better outcomes. Continuous research and enhanced awareness are crucial for improving diagnostic precision and treatment outcomes for UESL patients.

Indexed as

carcinosarcomashamartomasliver's mesenchymal tissuemesenchymalsarcomatoidundifferentiated embryonal sarcoma

Identifiers

PMID37829956
PMCPMC10565881
OpenAlexW4386603996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.