Evidence map›Paper›PMID 37829830›Full record

ArticleIranian endodontic journal2023

The Effect of Low-Frequency Pulsed Electromagnetic Fields on the Differentiation of Permanent Dental Pulp Stem Cells into Odontoblasts.

Saeed Rahimi, Mahnaz Ahrabi, Mohammad Samiei, Leila Roshangar, Behnaz Ahrabi, Behnam Hashemi, Shahriar Shahi, Naghmeh Rahimi Darehchi

Open access · greenAbstract read
In one paragraph

Article in Iranian endodontic journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Saeed RahimiDental and Periodontal Research Center, Endodontics Department, Tabriz Dental School, Tabriz University of Medical Sciences.
Mahnaz AhrabiEndodontics Department, Tabriz Dental School, Tabriz University of Medical Sciences, Iran.
Mohammad SamieiDental and Periodontal Research Center, Endodontics Department, Tabriz Dental School, Tabriz University of Medical Sciences.
Leila RoshangarStem Cell Research Center, Tabriz University of Medical Sciences, Iran.
Behnaz AhrabiLaser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Behnam HashemiStem Cell Research Center, Tabriz University of Medical Sciences, Iran.
Shahriar ShahiDental and Periodontal Research Center, Endodontics Department, Tabriz Dental School, Tabriz University of Medical Sciences.
Naghmeh Rahimi DarehchiDentistry Student, Semmelweis Dental School, Budapest, Hungary.
Tabriz University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Exposure to pulsed electromagnetic field (PEMF) has been revealed to affect the differentiation and proliferation of human mesenchymal stem cells derived from dental pulp multipotent stromal stem cells (DP-MSCs). This study aimed to investigate the differentiation effect of electromagnetic fields (EMFs) on the DP-MSC. Materials and Methods: PEMF was produced by a system comprising a multi-meter autotransformer, solenoid coils, and teslameter. This study included 10 groups of DP-MSCs which underwent different electromagnetic radiation time and beam intensity. Three samples tested for each group. The effect of PEMF with the intensity of 0.5 and 1 mT (mili Tesla) and 50 Hz on the proliferation rate of DP-MSC was evaluated at 20 and 40 minutes per day for seven days. MTT assay was applied to determine the growth and proliferation of DP-MSC. Gene expression of DMP1 for differentiation of DPSCs to odontoblasts was confirmed by Real Time PCR., ANOVA statistical analysis and Kruskal-Wallis test were used to analyze the data. Results: The survival in all exposure groups was significantly higher than that in control except in the group of 40 minutes, 1 mT ( Conclusions: The results obtained promise that in the future, by placing an important part of the pulp next to the electromagnetic field, the lost part of the pulp can be reconstructed and the dentin barrier can be created.

Indexed as

Bone Marrow Mesenchymal Stem CellsDental PulpDental Pulp-derived Mesenchymal Stem CellsPulsed Electromagnetic Field

Identifiers

PMID37829830
PMCPMC10565999
OpenAlexW4387600359

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.