Evidence map›Paper›PMID 37829756›Full record

ArticleNorthern clinics of Istanbul2023

Restrictive effects of thalassemia on respiratory functions: One center experience.

Gizem Zengin Ersoy, Ercan Nain, Mehtap Ertekin, Ozlem Terzi, Ayse Senay Sasihuseyinoglu, Gurcan Dikme

Open access · diamondAbstract read
In one paragraph

Article in Northern clinics of Istanbul, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gizem Zengin ErsoyDepartment of Pediatric Hematology Oncology, Pediatric Bone Marrow Transplantation Unit, Altinbas University, Medical Park Bahcelievler Hospital, Istanbul, Turkiye.
Ercan NainDepartment of Pediatric Allergy Immunology, Sanliurfa Training and Research Hospital, Sanliurfa, Turkiye.
Mehtap ErtekinDepartment of Pediatric Hematology Oncology, Sanliurfa Training and Research Hospital, Sanliurfa, Turkiye.
Ozlem TerziDepartment of Pediatric Hematology Oncology, Sanliurfa Training and Research Hospital, Sanliurfa, Turkiye.
Ayse Senay SasihuseyinogluDepartment of Pediatric Allergy Immunology, Sanliurfa Training and Research Hospital, Sanliurfa, Turkiye.
Gurcan DikmeDepartment of Pediatric Hematology Oncology, Sanliurfa Training and Research Hospital, Sanliurfa, Turkiye.
Altınbaş University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRespiratory functions in thalassemia major (TM) patients concerning poor chelation are a frequently researched issue. Our study aims to evaluate the lung functions of our patients with TM in the chronic transfusion program and to correlate them with their age, ferritin levels, and pre-transfusion hemoglobin values.

methodsHeight, weight, pulmonary function test (PFT) results, pre-transfusion hemoglobin levels, and ferritin levels of 97 patients (55 boys and 42 girls) without any underlying cardiac or chronic respiratory disease were recorded. PFT is consisted of forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), the ratio of FEV1/FVC to peak expiratory flow (PEF), and forced mid-exhaled flow between 25% and 75% of mid-expiratory flow (MEF

resultsLow FVC was observed in 58 patients (60%), and low FEV1 was observed in 26 patients (27.6%). Low PEF was observed in 62 patients (64.5%), and low MEF25-75 was observed in 8 (8.3%). PFT was affected in 75 patients (78.1%). The pattern of involvement was restrictive. Age, height, and ferritin values significantly affected the MEF

conclusionAge and height are the main risk factors affecting FEV1, MEF

Indexed as

Iron depositionpulmonary functionsthalassemia major

Identifiers

PMID37829756
PMCPMC10565749
OpenAlexW4387318703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.