Evidence map›Paper›PMID 37829605›Full record

ArticleOptica2021

High-resolution and sensitivity bi-directional x-ray phase contrast imaging using 2D Talbot array illuminators.

Alex Gustschin, Mirko Riedel, Kirsten Taphorn, Christian Petrich, Wolfgang Gottwald, Wolfgang Noichl, Madleen Busse, Sheila E Francis, Felix Beckmann, Jörg U Hammel and 3 more

Open access · goldAbstract read
In one paragraph

Article in Optica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 0 citations in OpenAlex.

  1. Quantitative Stain Mapping in X-Ray Virtual Histology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Alex GustschinDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.ORCID https://orcid.org/0000-0002-1559-5495
Mirko RiedelDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Kirsten TaphornDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.ORCID https://orcid.org/0000-0002-6160-3273
Christian PetrichDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Wolfgang GottwaldDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Wolfgang NoichlDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Madleen BusseDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.ORCID https://orcid.org/0000-0002-0114-2380
Sheila E FrancisDepartment of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield S10 2RX, UK.ORCID https://orcid.org/0000-0001-6552-0339
Felix BeckmannInstitute of Materials Physics, Helmholtz-Zentrum Hereon, Max-Planck-Str. 1, 21502 Geesthacht, Germany.
Jörg U HammelInstitute of Materials Physics, Helmholtz-Zentrum Hereon, Max-Planck-Str. 1, 21502 Geesthacht, Germany.ORCID https://orcid.org/0000-0002-6744-6811
Julian MoosmannInstitute of Materials Physics, Helmholtz-Zentrum Hereon, Max-Planck-Str. 1, 21502 Geesthacht, Germany.
Pierre ThibaultDepartment of Physics, University of Trieste, Trieste 34217, Italy.
Julia HerzenDepartment of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Technical University of Munich · DEUniversity of Sheffield · GBUniversity of Trieste · IT

Funding

British Heart Foundation PG/20/10010
6 · The paper itself

Abstract

Two-dimensional (2D) Talbot array illuminators (TAIs) were designed, fabricated, and evaluated for high-resolution high-contrast x-ray phase imaging of soft tissue at 10-20 keV. The TAIs create intensity modulations with a high compression ratio on the micrometer scale at short propagation distances. Their performance was compared with various other wavefront markers in terms of period, visibility, flux efficiency, and flexibility to be adapted for limited beam coherence and detector resolution. Differential x-ray phase contrast and dark-field imaging were demonstrated with a one-dimensional, linear phase stepping approach yielding 2D phase sensitivity using unified modulated pattern analysis (UMPA) for phase retrieval. The method was employed for x-ray phase computed tomography reaching a resolution of 3 µm on an unstained murine artery. It opens new possibilities for three-dimensional, non-destructive, and quantitative imaging of soft matter such as virtual histology. The phase modulators can also be used for various other x-ray applications such as dynamic phase imaging, super-resolution structured illumination microscopy, or wavefront sensing.

Identifiers

PMID37829605
PMCPMC10567101
OpenAlexW3161168934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.