Evidence map›Paper›PMID 37829201›Full record

ArticleiScience2023

Identification of optimal conditions for human placental explant culture and extracellular vesicle release.

Chandana Tekkatte, Scott A Lindsay, Erika Duggan, Anelizze Castro-Martínez, Abbas Hakim, Isabella Saldana, Yan Zhang, Jun Zhou, Rachel Sebastian, Yukun Liu and 7 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Crosstalk of extracellular vesicles in maternal-fetal interaction.Frontiers in cell and developmental biology · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Placental Origins of Preeclampsia: Insights from Multi-Omic Studies.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Chandana TekkatteDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Scott A LindsayDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Erika DugganScintillon Institute, San Diego, CA 92121, USA.
Anelizze Castro-MartínezDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Abbas HakimDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Isabella SaldanaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Yan ZhangDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Jun ZhouDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Rachel SebastianDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Yukun LiuDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Devin S PontigonDepartment of Pathology, University of California San Diego, La Jolla, CA 92037, USA.
Morgan MeadsSanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA.
Tzu Ning LiuDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
Donald P PizzoDepartment of Pathology, University of California San Diego, La Jolla, CA 92037, USA.
John NolanScintillon Institute, San Diego, CA 92121, USA.
Mana M ParastSanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA.
Louise C LaurentDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92037, USA.
University of California San Diego · USQingdao University · CNScintillon Institute · USSun Yat-sen University · CN

Funding

Reference Profiles of ExRNAs in Normal Human PregnancyU01HL126494 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LAURENT, LOUISE CHANG · 2014 to 2018
$3.4M
Human Trophoblast Stem Cells: the In Vivo Niche and Relationship to Pluripotent Stem CellsR01HD089537 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PARAST, MANA M · 2017 to 2021
$2.4M
Development and application of a scalable workflow for immunomagnetic separation of exRNA carrier subclasses and molecular analysis of their cargoUG3CA241687 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LAURENT, LOUISE CHANG · 2019 to 2020
$1.1M
NCI NIH HHS UG3 CA241687NHLBI NIH HHS U01 HL126494NICHD NIH HHS R01 HD089537
6 · The paper itself

Abstract

Extracellular vesicles (EVs) can mediate intercellular communication, including signaling between the placenta and maternal tissues. Human placental explant culture is a versatile

Indexed as

Biological sciencesCell biologyStem cell research

Identifiers

PMID37829201
PMCPMC10565782
OpenAlexW4387036499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.