Evidence map›Paper›PMID 37828915›Full record

ArticleBJPsych open2023

Multidisciplinary development of guidelines for ketamine treatment for treatment-resistant major depression disorder for use by adult specialist mental health services in New Zealand.

Ben Beaglehole, Paul Glue, Mike Clarke, Richard Porter

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ben BeagleholeDepartment of Psychological Medicine, University of Otago, New Zealand.ORCID https://orcid.org/0000-0002-9521-1745
Paul GlueDepartment of Psychological Medicine, University of Otago, New Zealand.
Mike ClarkeSpecialist Mental Health Services, Te Whatu Ora - Health New Zealand Waitaha Canterbury, New Zealand.
Richard PorterDepartment of Psychological Medicine, University of Otago, New Zealand.ORCID https://orcid.org/0000-0002-8695-3966
University of Otago · NZCanterbury District Health Board · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe evidence base for racemic ketamine treatment for treatment-resistant major depressive disorder (TRD) continues to expand, but there are major challenges translating this evidence base into routine clinical care.

aimTo prepare guidelines for ketamine treatment of TRD that are suitable for routine use by publicly funded specialist mental health services.

methodWe consulted with senior leadership, clinical pharmacy, psychiatrists, nursing, service users and Māori mental health workers on issues relating to ketamine treatment. We prepared treatment guidelines taking the evidence base for ketamine treatment and the consultation into account.

resultsKetamine treatment guidance is reported. This offers two treatment pathways, including a test of ketamine responsiveness with intramuscular ketamine and the dominant use of oral ketamine for a 3-month course to maximise the opportunity for the short-term benefits of ketamine to accumulate.

conclusionsWe have responded to the challenges of translating the evidence base for ketamine treatment into a form suitable for routine care.

Indexed as

evidence baseguidelinesKetamineoral ketamineprotocol

Identifiers

PMID37828915
PMCPMC10594164
OpenAlexW4387599946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.