Evidence map›Paper›PMID 37828903›Full record

ArticleGut microbes2023

Targeting hypoxia-inducible factor-1 alpha suppresses

Jennifer M Noto, M Blanca Piazuelo, Judith Romero-Gallo, Alberto G Delgado, Giovanni Suarez, Konstantina Akritidou, Miguel Girod Hoffman, Juan Carlos Roa, Cormac T Taylor, Richard M Peek

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. International journal of molecular medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. International journal of molecular sciences · 2025
    Article
  14. Microbiota and gastric cancer: from molecular mechanisms to therapeutic strategies.Frontiers in cellular and infection microbiology · 2025
    Review
  15. Article
  16. N6-methyladenosine modification of hypoxia-inducible factor-1α regulatesWorld journal of gastrointestinal oncology · 2024
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Jennifer M NotoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-3497-0676
M Blanca PiazueloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Judith Romero-GalloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Alberto G DelgadoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Giovanni SuarezDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Konstantina AkritidouDepartment of Biology, Davidson College, Davidson, NC, USA.
Miguel Girod HoffmanSchool of Medicine, University of Puerto Rico, San Juan, USA.ORCID 0000-0002-2114-6303
Juan Carlos RoaDepartment of Pathology, School of Medicine, Center for Cancer Prevention and Control (CECAN), Pontificia Universidad Catolica de Chile, Santiago, Chile.
Cormac T TaylorSchool of Medicine, Systems Biology Ireland and The Conway Institute, University College Dublin, Dublin, Ireland.
Richard M PeekDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · USDavidson College · USPontificia Universidad Católica de Chile · CLUniversity College Dublin · IEUniversity of Puerto Rico System · PR

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 2009 to 2026
$27.5M
H.Pylori Relationship to Digestive Diseases and CancerR01CA077955 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2003 to 2026
$9.7M
Helicobacter Pylori and Gastrointestinal BiologyR01DK058587 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEK, RICHARD M. · 2001 to 2024
$7.8M
Interactions Between the Microbiota and Helicobacter pylori in Gastric CarcinogenesisR01CA281732 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JAMES G FOX, RICHARD M. PEEK · 2023 to 2026
$2.7M
NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA077955NCI NIH HHS R01 CA281732NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK058587
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeHelicobacter InfectionsHelicobacter pyloriAnimalsHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitInflammationMiceVirulenceHypoxia-Inducible Factor 1, alpha Subunitdimethyloxalylglycine (DMOG)gastric cancergastric inflammationHelicobacter pylorihypoxia-inducible factor-1 alpha (HIF-1α)prolyl hydroxylase (PHD)

Identifiers

PMID37828903
PMCPMC10578190
OpenAlexW4387598303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.