Evidence map›Paper›PMID 37828583›Full record

ArticleTrials2023

Tailored interventions to improve adherence to medication in elderly patients with Parkinson's disease: a study protocol for a randomized controlled trial (AdhCare).

Sarah Mendorf, Ulrike Teschner, Thomas Lehmann, Tino Prell, Hannah Maria Mühlhammer

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sarah MendorfDepartment of Neurology, Jena University Hospital, Jena, Germany. sarah.mendorf@med.uni-jena.de.ORCID http://orcid.org/0000-0002-1297-6014
Ulrike TeschnerDepartment of Neurology, Jena University Hospital, Jena, Germany.
Thomas LehmannInstitute of Medical Statistics, Computer and Data Sciences, Jena University Hospital, Jena, Germany.
Tino PrellDepartment of Geriatrics, Halle University Hospital, Halle, Germany.
Hannah Maria MühlhammerDepartment of Neurology, Jena University Hospital, Jena, Germany.
Jena University Hospital · DEUniversity Hospital in Halle · DE

Funding

Bundesministerium für Bildung und Forschung 01GY1804Deutsche Forschungsgemeinschaft 413668513
6 · The paper itself

Abstract

backgroundNonadherence to medication is a major issue in patients with chronic disorders such as Parkinson's disease (PD). Many interventions for increasing adherence have been tested, and these have shown weak-to-moderate efficiency. Although the best methods to improve adherence remain unclear, it is reasonable to use tailored interventions instead of the "one-size-fits-all" approach.

methodsA randomized, controlled, triple-blinded trial in elderly patients with PD is conducted to test the efficacy of AdhCare, a tailored intervention to enhance adherence compared with that achieved with routine care (64 participants per arm). Motor function, quality of life, and adherence measures will be assessed at baseline and at 3 and 6 months of follow-up. The type of intervention depends on the main personal reason for nonadherence (e.g., forgetting to take the medication or poor knowledge about the medication). DISCUSSION: The results of this study will provide valuable information for health professionals and policymakers on the effectiveness of tailored interventions in elderly patients with PD.

trial registrationGerman Clinical Trials Register DRKS00023655. Registered on 24 February 2021. Last update on 22 March 2023.

Indexed as

Parkinson DiseaseAgedHumansMedication AdherenceQuality of LifeRandomized Controlled Trials as TopicResearch DesignAdherenceChronic diseasesInterventionMedicationParkinson’s diseaseRandomization

Identifiers

PMID37828583
PMCPMC10571350
OpenAlexW4387570642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.