Evidence map›Paper›PMID 37828581›Full record

ArticleFluids and barriers of the CNS2023

In vitro investigation of the effect of proinflammatory cytokines on mouse choroid plexus membrane transporters Ncbe and NKCC1.

Laura Øllegaard Johnsen, Kathrine Abildskov Friis, Helle Hasager Damkier

Open access · goldAbstract read
In one paragraph

Article in Fluids and barriers of the CNS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Molecular hallmarks of hydrocephalus.Science translational medicine · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Genetic and molecular mechanisms of hydrocephalus.Frontiers in molecular neuroscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura Øllegaard Johnsen *Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus, Denmark.
Kathrine Abildskov Friis *Department of Biomedicine, Faculty of Health, Aarhus University, Aarhus, Denmark.
Helle Hasager DamkierDepartment of Biomedicine, Faculty of Health, Aarhus University, Aarhus, Denmark. hd@biomed.au.dk.
Aarhus University · DK

Funding

Novo Nordisk Fonden NNF18OC0052038
6 · The paper itself

Abstract

Intraventricular hemorrhage is a potentially life-threatening condition. Approximately 20% of patients develop posthemorrhagic hydrocephalus with increased ventricular volume and intracranial pressure. Hydrocephalus develops partially due to increased secretion of cerebrospinal fluid by the choroid plexus. During hemorrhage a multitude of factors are released into the cerebrospinal fluid. Many of these have been implicated in the hypersecretion. In this study, we have investigated the isolated effect of inflammatory components, on the abundance of two membrane transporters involved in cerebrospinal fluid secretion by the choroid plexus: the Na

Indexed as

Choroid PlexusHydrocephalusAnimalsChloride-Bicarbonate AntiportersCytokinesHemorrhageInterleukin-6Membrane Transport ProteinsMiceSodium-Bicarbonate SymportersSolute Carrier Family 12, Member 2Tumor Necrosis Factor-alphaChloride-Bicarbonate AntiportersCytokinesInterleukin-6Membrane Transport ProteinsSlc12a2 protein, mouseSlc4a10 protein, mouseSodium-Bicarbonate SymportersSolute Carrier Family 12, Member 2Tumor Necrosis Factor-alphaCerebrospinal fluidIntraventricular hemorrhagePost-hemorrhagic hydrocephalus

Identifiers

PMID37828581
PMCPMC10568836
OpenAlexW4387595083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.