Evidence map›Paper›PMID 37828107›Full record

ArticleScientific reports2023

Impact of COVID infection on lung function test and quality of life.

Ming Ren Toh, Ying Rachel Teo, Li Choo Ruby Poh, Yiting Tang, Rui Ya Soh, Kiran Sharma, Ganesh Kalyanasundaram, Kai Chin Poh

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. The Effect of COVID-19 on Voice Quality: A Systematic Review.World journal of otorhinolaryngology - head and neck surgery · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients.International journal of environmental research and public health · 2025
    Article
  8. Functional Capacity Impairment in Long COVID After 17 Months of Severe Acute Disease.International journal of environmental research and public health · 2025
    Article
  9. Pulmonary manifestations of long COVID in Johannesburg, South Africa.Southern African journal of infectious diseases · 2025
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ming Ren TohDepartment of Internal Medicine, Sengkang General Hospital, Singapore, Singapore. mingren.toh@mohh.com.sg.
Ying Rachel TeoDepartment of Clinical Measurement Centre, Sengkang General Hospital, Singapore, Singapore.
Li Choo Ruby PohDepartment of Clinical Measurement Centre, Sengkang General Hospital, Singapore, Singapore.
Yiting TangDepartment of Internal Medicine, Sengkang General Hospital, Singapore, Singapore.
Rui Ya SohDepartment of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.
Kiran SharmaDepartment of Internal Medicine, Sengkang General Hospital, Singapore, Singapore.
Ganesh KalyanasundaramDepartment of Internal Medicine, Sengkang General Hospital, Singapore, Singapore.
Kai Chin PohDepartment of Internal Medicine, Sengkang General Hospital, Singapore, Singapore.
Sengkang General Hospital · SGSingapore General Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-COVID-19 pulmonary sequalae are well-recognized early in the pandemic. Survivorship clinics are crucial for managing at-risk patients. However, it is unclear who requires pulmonary function test (PFT) and when PFTs should be performed. We aim to investigate for whom and how these interval PFTs should be performed. We performed a single-centre, prospective cohort study on COVID-19 survivors between 1st May 2020 and 31st April 2022. These patients were followed up at 6, 9 and 12 months with interval PFT and Short Form-36 (SF-36) Health Survey. Those with PFT defects were offered a computed tomography scan of the thorax. Of the 46 patients recruited, 17 (37%) had severe/critical illness. Compared to those with mild/moderate disease, these patients were more likely to experience DLCO defects (59% versus 17%, p = 0.005) and had lower SF-36 scores (mean physical component summary score of 45 ± 12 versus 52 ± 8, p = 0.046). These differences were most notable at 6 months, compared to the 9- and 12-months intervals. DLCO defects were also associated with older age, raised inflammatory markers and extensive CXR infiltrates. Besides interstitial-like abnormalities, obesity and undiagnosed lung conditions accounted for 39% of the PFT abnormalities. Interval PFTs can be performed earliest 6 months post-COVID-19. Patients with normal tests were unlikely to develop new abnormalities and would not require repeat PFTs. Abnormal PFTs can be followed-up with repeat PFTs 6 monthly until resolution. Non-COVID-19 differentials should be considered for persistent PFT abnormalities.

Indexed as

COVID-19Quality of LifeHumansLungProspective StudiesRespiratory Function Tests

Identifiers

PMID37828107
PMCPMC10570308
OpenAlexW4387577180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.