ArticleScientific reports2023
A neural signature of social support mitigates negative emotion.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Maternal Social Support Reshapes the Offspring Brain Transcriptome to Buffer Prenatal Stress in Mice.Research square · 2026Article
- Modulation of interbrain synchrony by emotional valence and maternal presence in mother-child dyads: neural links to empathy and attachment.Scientific reports · 2026Article
- A comparative study of cognitive function among children with coeliac disease and healthy controls.Scientific reports · 2026Article
- Bridging the empathy perception gap fosters social connection.Nature human behaviour · 2025Article
- Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Mobile phone addiction and negative emotions: an empirical study among adolescents in Jiangxi Province.Frontiers in psychiatry · 2025Article
- Emotion Regulation Under Stress: A Social Processing and Memory Perspective.Current topics in behavioral neurosciences · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Social support can mitigate the impact of distressing events. Such stress buffering elicits activity in many brain regions, but it remains unclear (1) whether this activity constitutes a stable brain signature, and (2) whether brain activity can predict buffering across people. Here, we developed a neural signature that predicted social buffering of negative emotion in response to real life stressors. During neuroimaging, participants (n = 95) responded to stressful autobiographical memories either naturally, or by imagining a conversation with a peer. Using supervised dimensionality reduction and machine learning techniques, we identified a spatio-temporal neural signature that distinguished between these two trials. Activation of this signature was associated with less negative affect across trials, and people who most activated the signature reported more supportive social connections and lower loneliness outside the lab. Together, this work provides a behaviorally relevant neurophysiological marker for social support that underlies stress buffering.
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