Evidence map›Paper›PMID 37827919›Full record

Observational studyJournal of cardiothoracic and vascular anesthesia2024

Cannula-Associated Deep Vein Thrombosis After Venovenous Extracorporeal Membrane Oxygenation in Patients with and Without Systemic Anticoagulation.

Yang Gu, Milica Bjelic, Kunal Panda, Asad Ali Usman, Ryan Magnuson, Igor Gosev

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic and vascular anesthesia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Yang GuDepartment of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, MN. Electronic address: Yang_Gu@urmc.rochester.edu.
Milica BjelicDepartment of Anesthesiology, St Elizabeth Medical Center, Boston, MA.
Kunal PandaDepartment of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, MN.
Asad Ali UsmanDepartment of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA.
Ryan MagnusonDepartment of Surgery, Division of Cardiac Surgery, University of Rochester, Rochester, NY.
Igor GosevDepartment of Surgery, Division of Cardiac Surgery, University of Rochester, Rochester, NY.
University of Rochester · USHospital of the University of Pennsylvania · USSt. Elizabeth's Medical Center · USUniversity of Minnesota Rochester · USUniversity of Rochester Medical Center · US

Funding

NHLBI NIH HHS L30 HL159698
6 · The paper itself

Abstract

objectiveTo identify and compare the rates of cannula-associated deep vein thrombosis (CaDVT) in patients on venovenous extracorporeal membrane oxygenation (VV-ECMO) who receive systemic anticoagulation (AC) and those who do not receive AC.

designRetrospective observational study.

settingTertiary academic medical center.

participantsConsecutive patients who successfully have been decannulated from VV-ECMO for treatment of refractory acute respiratory distress syndrome between 2017 and 2022.

interventionsNone. MEASUREMENTS AND MAIN

resultsAfter decannulation of ECMO, a duplex sonograph was performed on the cannulation sites to determine the incidence and characteristics of cannula-related thrombosis. Thrombosis was classified as occlusive or nearly occlusive. Ninety-four of 161 patients were weaned from VV-ECMO. Nineteen patients who were placed on VV-ECMO due to COVID-19 were excluded. Twenty-seven of 52 patients (52%) who did not receive AC were identified to have thrombus. Twelve of 23 patients (52%) who received AC were identified to have thrombus. Patients who received AC required more blood products during the ECMO run and required longer support on VV-ECMO.

conclusionThis study showed a high incidence of cannula-related venous thrombosis after VV-ECMO decannulation. Surprisingly, the incidence of CaDVT in anticoagulation-free patients was the same as in patients requiring anticoagulation. Anticoagulated patients required longer support on VV-ECMO and required more transfusions. Routine post-decannulation screening for DVT is recommended due to the high incidence of CaDVT.

Indexed as

Extracorporeal Membrane OxygenationThrombosisVenous ThrombosisAnticoagulantsCannulaHumansRetrospective StudiesAnticoagulantsacute respiratory distress syndromeanticoagulantcompilationsdeep vein thrombosisextracorporeal membrane oxygenationVV-ECMO

Identifiers

PMID37827919
PMCPMC11788865
OpenAlexW4386780729

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.