Evidence map›Paper›PMID 37827707›Full record

ArticleInternational journal of spine surgery2023

The Effect of Preoperative, Low-Dose Intrathecal Morphine on Patient Outcomes Following Lumbar Fusion Surgery: Can We Teach an Old Dog New Tricks?

Samantha N Baxter, Jane C Brennan, Andrea H Johnson, Laura Stock, Regan King, Jake Gelfand, Kristina Andersen, Karen M Pipkin, Justin Turcotte, Chad M Patton

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of spine surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Samantha N BaxterDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Jane C BrennanDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Andrea H JohnsonDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Laura StockDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Regan KingDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Jake GelfandDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Kristina AndersenDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Karen M PipkinDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Justin TurcotteDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA jturcotte@aahs.org.
Chad M PattonDepartment of Orthopedics, Anne Arundel Medical Center, Annapolis, MD, USA.
Anne Arundel Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly pain control after lumbar fusion presents a challenge to patients and providers. Intrathecal morphine (ITM) has been used at the end of these procedures with limited benefit, but recent data suggest low-dose ITM at case initiation may be effective. This study aims to evaluate the use of preoperative ITM during lumbar fusion to determine whether there is a benefit for these patients.

methodsOne hundred and eighty lumbar fusion patients between 1 January 2018 and 31 May 2022 were evaluated. Patients were grouped by whether they received preoperative, low-dose ITM or not. Outcomes of interest included hospital narcotic consumption, pain scores, opioid-related complications, and complications within the first 90 days.

resultsSixty-five study patients received 200 µg ITM at case initiation and 115 did not. No differences in length of stay, discharge disposition, or complications in the first 90 days were noted. ITM patients received fewer milligram morphine equivalents in the postanesthesia care unit (9.7 ± 31.23 vs 21.83 ± 21.07;

conclusionsITM appears to be safe and effective for reducing early pain and narcotic consumption on the day of surgery for lumbar fusion patients and may hold value for incorporation into rapid recovery protocols and for improving pain-related patient satisfaction. CLINICAL RELEVANCE: ITM appears to be safe and effective for reducing early pain and narcotic consumption on the day of surgery for lumbar fusion patients and may hold value for incorporation into rapid recovery protocols and for improving pain-related patient satisfaction. LEVEL OF EVIDENCE: 3:

Indexed as

intrathecal morphinelumbar fusionnarcoticsoutcomespain control

Identifiers

PMID37827707
PMCPMC10623676
OpenAlexW4387580646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.