Evidence map›Paper›PMID 37824652›Full record

ArticleScience (New York, N.Y.)2023

Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon.

Nicola Micali, Shaojie Ma, Mingfeng Li, Suel-Kee Kim, Xoel Mato-Blanco, Suvimal Kumar Sindhu, Jon I Arellano, Tianliuyun Gao, Mikihito Shibata, Kevin T Gobeske and 4 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 3 countries.

Nicola Micali *Department of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0009-0002-2936-4708
Shaojie Ma *Department of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-8782-3047
Mingfeng Li *Department of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-7959-6008
Suel-Kee KimDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-0240-9304
Xoel Mato-BlancoHospital del Mar Research Institute, Parc de Recerca Biomèdica de Barcelona (PRBB), 08003 Barcelona, Catalonia, Spain.ORCID 0000-0003-2155-9922
Suvimal Kumar SindhuDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-7461-3104
Jon I ArellanoDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-9840-5756
Tianliuyun GaoDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-6261-8303
Mikihito ShibataDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.
Kevin T GobeskeDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.
Alvaro DuqueDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.
Gabriel SantpereHospital del Mar Research Institute, Parc de Recerca Biomèdica de Barcelona (PRBB), 08003 Barcelona, Catalonia, Spain.ORCID 0000-0001-5909-8637
Nenad SestanDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0003-0966-9619
Pasko RakicDepartment of Neuroscience, Yale School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-6963-0508
Yale University · USBarcelona Biomedical Research Park · ES

Funding

M-SCORCH: Methamphetamine use disorder data generation center for Single Cell Opioid Responses in the Context of HIVU01DA053628 · NIDA · YALE UNIVERSITY · PI HO, YA-CHI, SESTAN, NENAD · 2021 to 2025
$9.5M
Origin of Cortical Species-specific Distinctions.R01DA023999 · NIDA · YALE UNIVERSITY · PI RAKIC, PASKO · 2008 to 2019
$7.9M
1/2 Cell Type and Region-Specific Regulatory Networks in Human Brain Development and DisordersU01MH116488 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2018 to 2022
$6.5M
Origin of Cortical Species-specific DistinctionsR37DA023999 · NIDA · YALE UNIVERSITY · PI PASKO RAKIC · 2020 to 2026
$5.6M
Yale Macaque Brain ResourceR01MH113257 · NIMH · YALE UNIVERSITY · PI Alvaro Duque · 2017 to 2026
$4.3M
Developmental cell census of human and non-human primate brainU01MH124619 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2020 to 2022
$3.3M
1/2 Identification and Validation of Expression Quantitative Trait Loci (eQTLs) in discrete cell types across human brain developmentR01MH122678 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2023 to 2025
$2.2M
Identification of Genetic and Molecular Bases of Derived Phenotypes in Primate Brain DevelopmentR01HG010898 · NHGRI · YALE UNIVERSITY · PI SANTPERE BARO, GABRIEL, SESTAN, NENAD · 2020 to 2023
$2.2M
1/2 Identification and Validation of Expression Quantitative Trait Loci (eQTLs) in discrete cell types across human brain developmentU01MH122678 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2021 to 2022
$1.4M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
NHGRI NIH HHS R01 HG010898NIDA NIH HHS R01 DA023999NIDA NIH HHS R37 DA023999NIDA NIH HHS U01 DA053628NIH HHS S10 OD030363NIMH NIH HHS R01 MH113257NIMH NIH HHS R01 MH122678NIMH NIH HHS U01 MH116488NIMH NIH HHS U01 MH122678NIMH NIH HHS U01 MH124619
6 · The paper itself

Abstract

During early telencephalic development, intricate processes of regional patterning and neural stem cell (NSC) fate specification take place. However, our understanding of these processes in primates, including both conserved and species-specific features, remains limited. Here, we profiled 761,529 single-cell transcriptomes from multiple regions of the prenatal macaque telencephalon. We deciphered the molecular programs of the early organizing centers and their cross-talk with NSCs, revealing primate-biased galanin-like peptide (

Indexed as

Neural Stem CellsNeurogenesisTelencephalonAnimalsBrain NeoplasmsFemaleGalanin-Like PeptideGene Expression Regulation, DevelopmentalMacacaMental DisordersNervous System DiseasesNeuronsPregnancyGalanin-Like Peptide

Identifiers

PMID37824652
PMCPMC10705812
OpenAlexW4387568524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.