Evidence map›Paper›PMID 37824527›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

A nonequilibrium allosteric model for receptor-kinase complexes: The role of energy dissipation in chemotaxis signaling.

David Hathcock, Qiwei Yu, Bernardo A Mello, Divya N Amin, Gerald L Hazelbauer, Yuhai Tu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Nature physics · 2026
    Article
  4. Article
  5. ChemotaxingbioRxiv : the preprint server for biology · 2025
    Article
  6. ChemotaxingArXiv · 2025
    Article
  7. A chemoreceptor conformational equilibrium controlled by signaling inputs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. The structural logic of dynamic signaling in the Escherichia coli serine chemoreceptor.Protein science : a publication of the Protein Society · 2024
    Article
  9. Article
  10. The Structural Logic of Dynamic Signaling in thebioRxiv : the preprint server for biology · 2024
    Article
  11. Signal integration in chemoreceptor complexes.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

David Hathcock *IBM T. J. Watson Research Center, Yorktown Heights, NY 10598.ORCID 0000-0003-4551-9239
Qiwei Yu *IBM T. J. Watson Research Center, Yorktown Heights, NY 10598.ORCID 0000-0003-0610-3484
Bernardo A MelloInternational Center of Physics, Physics Institute, University of Brasilia, Brasilia 70919-970, Brazil.ORCID 0000-0002-9261-8013
Divya N AminDepartment of Biochemistry, University of Missouri, Columbia, MO 65211.ORCID 0009-0005-6470-0772
Gerald L HazelbauerDepartment of Biochemistry, University of Missouri, Columbia, MO 65211.ORCID 0000-0003-2449-2663
Yuhai TuIBM T. J. Watson Research Center, Yorktown Heights, NY 10598.ORCID 0000-0002-4589-981X
IBM (United States) · USUniversity of Missouri · USUniversidade de Brasília · BR

Funding

Molecular Studies of Chemoreception: Administrative Supplement for EquipmentR37GM029963 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI HAZELBAUER, GERALD L. · 2012 to 2021
$5.7M
Molecular Mechanisms and Biochemical Circuits for Adaptation in Biological SystemsR35GM131734 · NIGMS · IBM THOMAS J. WATSON RESEARCH CENTER · PI TU, YUHAI · 2019 to 2024
$1.8M
NIGMS NIH HHS R35 GM131734NIGMS NIH HHS R37 GM029963
6 · The paper itself

Abstract

The

Indexed as

ChemotaxisEscherichia coli ProteinsBacterial ProteinsEscherichia coliHistidine KinaseLigandsMethyl-Accepting Chemotaxis ProteinsSignal TransductionBacterial ProteinsEscherichia coli ProteinsHistidine KinaseLigandsMethyl-Accepting Chemotaxis Proteinsallosteric modelbacterial chemotaxiskinase activityligand bindingnonequilibrium systems

Identifiers

PMID37824527
PMCPMC10589639
OpenAlexW4387569024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.