ReviewPLoS pathogens2023
Mechanistic insights into the interaction between the host gut microbiome and malaria.
Review in PLoS pathogens, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- The symbiotic Wolbachia in Anopheles and its role in reducing the transmission of Plasmodium: updates and prospects.Archives of microbiology · 2026Review
- The gut microbiome in early life predicts malaria susceptibility.Frontiers in cellular and infection microbiology · 2026Article
- Analyzing human gut microbiome data from global populations: challenges and resources.Trends in microbiology · 2025Review
- Cerebral manifestations of falciparum malaria in adults: more than meets the eye.Trends in parasitology · 2025Review
- Low prevalence of helminth infection in Ugandan children hospitalized with severe malaria.PloS one · 2025Article
- Gut microbiota composition differences are associated with geographic location and age in malaria-endemic regions of Rwanda.PloS one · 2025Observational
- RepeatedFrontiers in microbiology · 2025Article
- Multi-omics profiling reveals associations between gut microbiota and olfactory gene expression in mosquitoes.Frontiers in cellular and infection microbiology · 2025Article
- Low prevalence of soil transmitted helminth infection in Ugandan children hospitalized with severe malaria.medRxiv : the preprint server for health sciences · 2024Article
- The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria.Nature reviews. Immunology · 2024Review
- The microbiota: a crucial mediator in gut homeostasis and colonization resistance.Frontiers in microbiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Malaria is a devastating infectious disease and significant global health burden caused by the bite of a Plasmodium-infected female Anopheles mosquito. Gut microbiota was recently discovered as a risk factor of severe malaria. This review entails the recent advances on the impact of gut microbiota composition on malaria severity and consequence of malaria infection on gut microbiota in mammalian hosts. Additionally, this review provides mechanistic insight into interactions that might occur between gut microbiota and host immunity which in turn can modulate malaria severity. Finally, approaches to modulate gut microbiota composition are discussed. We anticipate this review will facilitate novel hypotheses to move the malaria-gut microbiome field forward.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.