Evidence map›Paper›PMID 37824328›Full record

ArticleCell reports2023

Essential role of Mg

Neha Gupta, Cristina Soriano-Úbeda, Paula Stein, Virginia Savy, Brian N Papas, Goli Ardestani, Ingrid Carvacho, Dominique Alfandari, Carmen J Williams, Rafael A Fissore

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The TRPV3 channel is a mediator of zinc influx and homeostasis in murine oocytes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. MgJournal of cellular physiology · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Neha GuptaDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Cristina Soriano-ÚbedaDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA; Department of Veterinary Medicine, Surgery, and Anatomy, Veterinary School, University of León, León, Spain.
Paula SteinReproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Virginia SavyReproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Brian N PapasIntegrative Bioinformatics Support Group, Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Goli ArdestaniDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA; Clinical Research Embryologist, Boston IVF, Waltham, MA, USA.
Ingrid CarvachoFaculty of Medicine, Universidad Católica del Maule, Talca, Chile.
Dominique AlfandariDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Carmen J WilliamsReproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Rafael A FissoreDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: rfissore@umass.edu.
University of Massachusetts Amherst · USNational Institutes of Health · USCatholic University of the Maule · CL

Funding

Environmental influence on reproductive tract functionZIAES102405 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILLIAMS, CARMEN · 2009 to 2025
$20.6M
Mechanism of Xenopus Cranial Neural Crest Cell MigrationR01DE016289 · NIDCR · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ALFANDARI, DOMINIQUE R · 2006 to 2022
$5.4M
Regulation of the functional expression of the TRPM7 chanzyme essential for Mg2+ homeostasis in mouse oocytes and cleaving embryos to improve assisted reproductive technologies and modulate fertilityR01HD092499 · NICHD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Rafael Antonio Fissore · 2018 to 2026
$2.0M
Production and characterization of monoclonal antibodies to Xenopus ProteinsR24OD021485 · OD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ALFANDARI, DOMINIQUE R · 2017 to 2020
$1.2M
Intramural NIH HHS ZIA ES102405NICHD NIH HHS R01 HD092499NIDCR NIH HHS R01 DE016289NIH HHS R24 OD021485
6 · The paper itself

Abstract

TRPM7 (transient receptor potential cation channel subfamily M member 7) is a chanzyme with channel and kinase domains essential for embryo development. Using gamete-specific Trpm7-null lines, we report that TRPM7-mediated Mg

Indexed as

Embryonic DevelopmentMagnesiumTRPM Cation ChannelsAnimalsCytoplasmGene Expression RegulationGerm CellsMiceMagnesiumTrpm7 protein, mouseTRPM Cation ChannelsARTCa(2+) oscillationsCP: Cell biologyCP: Developmental biologyeggsfertilizationmammalsnuclear localizationoocytesoxidative stressspermZn(2+)

Identifiers

PMID37824328
PMCPMC10842026
OpenAlexW4387536659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.