Evidence map›Paper›PMID 37823667›Full record

ArticleJournal of clinical microbiology2023

Detailed β-(1→3)-D-glucan and mannan antigen kinetics in patients with candidemia.

Johannes Träger, Sarah Dräger, Sidonia Mihai, Franziska Cipa, Andrea Busse Grawitz, Thomas Epting, Renate Meyer, Elfriede Rappold, Jürgen Held

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Brazilian guidelines for the diagnosis and treatment of candidemia and invasive candidiasis in adults and children.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Guideline
  2. Diagnostic performance of β-(1→3)-D-glucan, twoJournal of clinical microbiology · 2026
    Trial
  3. Review
  4. Article
  5. Early-Onset Candidemia in Adult Intensive Care Units.Diagnostics (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Johannes TrägerMikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg , Erlangen, Germany.
Sarah DrägerKlinik für Innere Medizin, Universitätsspital Basel , Basel, Switzerland.ORCID 0000-0001-9410-7404
Sidonia MihaiZentrallabor, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg , Erlangen, Germany.
Franziska CipaZentrallabor, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg , Erlangen, Germany.
Andrea Busse GrawitzInstitut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinikum Freiburg , Freiburg, Germany.
Thomas EptingInstitut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinikum Freiburg , Freiburg, Germany.
Renate MeyerInstitut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum Freiburg , Freiburg, Germany.
Elfriede RappoldInstitut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum Freiburg , Freiburg, Germany.
Jürgen HeldMikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg , Erlangen, Germany.ORCID 0000-0003-1130-9727
Universitätsklinikum Erlangen · DEUniversity Medical Center Freiburg · DEUniversity Hospital of Basel · CH

Funding

Deutsche Forschungsgemeinschaft (DFG) HE 8209/1-1Pfizer (Pfizer Inc.) WI179471
6 · The paper itself

Abstract

Fungal antigens such as β-(1→3)-D-glucan (BDG) or mannan (Mn) are useful for detection of candidemia. However, detailed data on serum levels before diagnosis and during treatment are scarce. We conducted a prospective study at two German tertiary care centers for 36 months. Sera from adult patients with candidemia were tested for BDG (Fungitell assay) and Mn (Platelia

Indexed as

beta-GlucansCandidemiaAdultAntigens, FungalBiomarkersGlucansHumansMannansProspective StudiesRecurrenceSensitivity and SpecificityAntigens, Fungalbeta-GlucansBiomarkersGlucansMannansbiomarkerCandidaFungitellglucanmannanPlateliasepsis

Identifiers

PMID37823667
PMCPMC10662340
OpenAlexW4387563761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.