Evidence map›Paper›PMID 37823125›Full record

ArticleFood science & nutrition2023

Effects of resveratrol on tolerance to ischemia/reperfusion injury in aged male mice: Role of autophagy and apoptosis.

Xiaogang Song, Chao Wei, Hui Huang, Xingdan Cao, Ziyi Chen, Yongqing Chen, Bing Wu

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Xiaogang SongKey Laboratory of Stem Cells and Gene Drugs of Gansu Province, Department of Cardiology The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China.ORCID https://orcid.org/0000-0002-6528-955X
Chao WeiDepartment of Neurology The First Medical Center of the Chinese People's Liberation Army General Hospital Beijing China.
Hui HuangDepartment of Geriatrics The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China.
Xingdan CaoKey Laboratory of Stem Cells and Gene Drugs of Gansu Province, Department of Cardiology The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China.
Ziyi ChenKey Laboratory of Stem Cells and Gene Drugs of Gansu Province, Department of Cardiology The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China.
Yongqing ChenDepartment of Cardiology The Gansu Provincial Central Hospital Lanzhou China.
Bing WuDepartment of Geriatrics The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army Lanzhou China.
181st Hospital of Chinese People's Liberation Army · CNPeople's Liberation Army 401 Hospital · CNChinese PLA General Hospital · CNGansu Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aged myocardium is more susceptible to ischemia/reperfusion (I/R) injury. Autophagy and apoptosis play important roles in cardiac I/R injury. However, whether resveratrol can reduce the I/R vulnerability of aged myocardium by regulating apoptosis and autophagy remains unclear. The present study aimed to investigate the effect of resveratrol on the tolerance to I/R injury in aged male mice and to determine the contribution of apoptosis and autophagy. We used aged C57 mice as our research subjects. The hearts of mice were isolated after 6 weeks of intragastric administration with resveratrol and subsequently perfused with Krebs-Henseleit buffer to produce the I/R model. We found that resveratrol alleviated cardiac I/R injury in aged mice, but not in SIRT1

Indexed as

agedapoptosisautophagyischemia/reperfusion injuryresveratrol

Identifiers

PMID37823125
PMCPMC10563695
OpenAlexW4382398681

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.