Evidence map›Paper›PMID 37823111›Full record

ArticleFood science & nutrition2023

Tibetan tea reduces obesity brought on by a high-fat diet and modulates gut flora in mice.

Gang He, Tangcong Chen, Lifen Huang, Yiyuan Zhang, Yanjiao Feng, Qijun Liu, Xiaojing Yin, Shaokui Qu, Chen Yang, Jianghong Wan and 3 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gang HeKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.ORCID https://orcid.org/0000-0001-5026-1493
Tangcong ChenKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.ORCID https://orcid.org/0000-0002-6839-6844
Lifen HuangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Yiyuan ZhangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Yanjiao FengKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Qijun LiuKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Xiaojing YinKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Shaokui QuKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Chen YangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Jianghong WanKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Li LiangKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Jun YanKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.
Wei LiuKey Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University Chengdu China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been shown that Tibetan tea (TT) inhibits obesity and controls lipid metabolism. The fundamental processes by which TT prevents obesity are yet entirely unknown. Consequently, this research aimed to ascertain if TT may prevent obesity by modifying the gut flora. Our research demonstrated that TT prevented mice from gaining weight and accumulating fat due to the high-fat diet (HFD), decreased levels of blood total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), and raised levels of high-density lipoprotein cholesterol (HDL-C). Adipogenesis-related genes such as acetyl-Coenzyme A carboxylase 1 (ACC1, LOC107476), fatty acid synthase (Fas, LOC14104), sterol regulatory element-binding protein-1c (SREBP-1c, LOC20787), CCAAT/enhancer-binding protein α (C/EBPα, LOC12606), stearoyl-CoA desaturase 1 (SCD1, LOC20249), and peroxisome proliferator-activated receptor γ (PPARγ, LOC19016) had their expression downregulated by lowering the

Indexed as

gut florahigh‐fat dietobesityshort‐chain fatty acidsTibetan tea

Identifiers

PMID37823111
PMCPMC10563754

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.