Evidence map›Paper›PMID 37822814›Full record

ArticleBioinformation2023

SWATH-MS analysis of plasma proteins among Indian HIV-1 infected patients.

Sushanta Kumar Barik, Srikanth Prasad Tripathy, Deepa Bisht, Praveen Singh, Rahul Chakraborty, Shripad A Patil, Tej Pal Singh, Deepika Varshney, Srikanta Jena, Keshar Kunja Mohanty

Open access · hybridAbstract read
In one paragraph

Article in Bioinformation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sushanta Kumar BarikICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, Uttar-Pradesh, India-282004.
Srikanth Prasad TripathyICMR-National Institute for Research in Tuberculosis, Chetpet, Chennai, Tamil Nadu, India-600031.
Deepa BishtICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, Uttar-Pradesh, India-282004.
Praveen SinghCSIR-Institute of Genomics and Integrative Biology, CSIR, New Delhi-110025.
Rahul ChakrabortyCSIR-Institute of Genomics and Integrative Biology, CSIR, New Delhi-110025.
Shripad A PatilICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, Uttar-Pradesh, India-282004.
Tej Pal SinghSarojini Naidu Medical College, Agra, Uttar-Pradesh, India-282003.
Deepika VarshneyICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, Uttar-Pradesh, India-282004.
Srikanta JenaRavenshaw University, Odisha, Cuttack, India - 753003.
Keshar Kunja MohantyICMR-National JALMA Institute for Leprosy and Other Mycobacterial Diseases, Agra, Uttar-Pradesh, India-282004.
National JALMA Institute for Leprosy & Other Mycobacterial Diseases · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification and characterization of plasma proteins in drug resistant and drug sensitive in HIV-1 infected/AIDS patients were carried out using the SWATH-MS protocol. In total, 204 proteins were identified and quantified, 57 proteins were differentially expressed, out of which 25 proteins were down regulated and 32 proteins were up regulated in drug resistant patients. Six proteins such as complement C4-A, immunoglobulin heavy variable 1-2, carboxylic ester hydrolase, fibulin-1, immunoglobulin lambda constant7, secreted phosphoprotein 24 were differentially expressed in individuals with drug resistant HIV as compared to individuals with drug sensitive HIV. Gene ontology of 57 differentially expressed proteins was analysed and documented.

Indexed as

AIDS, ARTHIV-1NNRTINRTISWATH-MS

Identifiers

PMID37822814
PMCPMC10563564
OpenAlexW4387563881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.