ReviewInternet interventions2023
Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis.
Review in Internet interventions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The improvement of umbilical cord mesenchymal stem cells on the ovarian microenvironment: a systematic review and meta-analysis.Journal of ovarian research · 2026Pooled it
- The intervention effect of internet-based cognitive behavioral therapy on anxiety, depression, and stress in college students: a systematic review and meta-analysis based on randomized controlled trials.Frontiers in psychology · 2026Pooled it
- Strength-based capacity-building interventions to promote adolescents' mental health: A systematic review and meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Comparative effectiveness and acceptability of internet-based psychological interventions on depression in young people: a systematic review and network meta-analysis.BMC psychiatry · 2025Pooled it
- Effectiveness of internet-based self-help interventions for depression in adolescents and young adults: a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Therapist-guided and self-guided internet-based behavioural activation versus treatment as usual for adolescents with depression: randomised controlled trial with economic evaluation.BMJ mental health · 2026Trial
- Evaluation of Two Web-Based Interventions (REMOTION and Res-Up!) for Clients From Psychotherapy Waitlists in Routine Outpatient Psychotherapy (Therapy Online Plus-TOP): Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Emotion regulation and social information processing as targets of a guided selective prevention app for emerging adults with a history of adverse childhood experiences: A randomised controlled trial.Internet interventions · 2026Article
- Comparative efficacy of digital health interventions for depression and anxiety symptoms in adolescents and young adults: a systematic review and bayesian network meta-analysis.Child and adolescent psychiatry and mental health · 2026Article
- Twelve-month outcomes and comparative costs of internet-delivered psychodynamic therapy versus cognitive-behavioral therapy for adolescent depression: a randomized controlled trial.Frontiers in psychiatry · 2026Article
- A Brief, Affordable, Broad-Access Transdiagnostic Intervention (Project RE-THINK) for Adolescents: Quasi-Experimental Study.JMIR mental health · 2025Article
- Designing Chatbots to Treat Depression in Youth: Qualitative Study.JMIR human factors · 2025Article
- Digital interventions in mental health: An overview and future perspectives.Internet interventions · 2025Review
- Randomized trial testing a self-guided digital mental health intervention teaching calming skills for Ukrainian children.Npj mental health research · 2025Article
- Pathophysiological Insights and Multimodal Interventions in Chronic Tinnitus, Anxiety, and Sleep Disorders.Nature and science of sleep · 2025Review
- Multidisciplinary perspectives on personalised prevention in youth mental health.Frontiers in digital health · 2025Article
- Effects of acupuncture and moxibustion on ulcerative colitis: An overview of systematic reviews.Heliyon · 2024Article
- Feasibility of a trauma-focused internet- and mobile-based intervention for youth with posttraumatic stress symptoms.European journal of psychotraumatology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Internet-based cognitive behavior therapy (ICBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in adolescents is limited. This systematic review and meta-analysis aims to comprehensively assess the efficacy of ICBT in addressing depression among adolescents. Methods: Four electronic databases were searched on June 8, 2023. Randomized controlled trials (RCTs) evaluating the efficacy of ICBT for depression in adolescents were included. The quality of the studies was assessed using the risk of bias tool recommended by the Cochrane Handbook. Furthermore, the GRADE approach was employed to gauge the certainty of the obtained evidence. Meta-analysis was conducted using RevMan 5.4, and Egger's test was implemented through Stata for assessment of potential publication bias. Results: A total of 18 RCTs involving 1683 patients were included. In comparison to control groups like attention control, waiting list, and treatment as usual, our meta-analysis findings elucidate a significant reduction in depression scores (SMD = -0.42, 95 % CI: [-0.74, -0.11], Conclusion: Results provide evidence of the efficacy of ICBT to reduce depressive and anxiety symptoms in adolescents. These research findings are of vital significance for the establishment of evidence-based treatment guidelines in the digital era. Trial registration: PROSPERO registration: CRD42021277562.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.