Evidence map›Paper›PMID 37822563›Full record

ArticleResearch and practice in thrombosis and haemostasis2023

Venous thromboembolism prevention in cancer care: implementation strategies to address underuse.

Karlyn A Martin, Kenzie A Cameron, Madison J Lyleroehr, Jeffrey A Linder, Matt O'Brien, Lisa R Hirschhorn

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Implementation failure: thromboprophylaxis in ambulatory patients with cancer.Hematology. American Society of Hematology. Education Program · 2025
    Review
  2. Article
  3. Time to move beyond risk assessment models for ambulatory cancer-associated thrombosis.Research and practice in thrombosis and haemostasis · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karlyn A MartinDepartment of Medicine, Division of Hematology and Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Kenzie A CameronDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Madison J LyleroehrDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Jeffrey A LinderDepartment of Medicine, Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Matt O'BrienDepartment of Medicine, Division of General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Lisa R HirschhornDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

USC-Yale Roybal Center for Behavioral Interventions in AgingP30AG024968 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JASON N. DOCTOR · 2004 to 2026
$14.7M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LINDER, JEFFREY A., WOLF, MICHAEL S · 2020 to 2024
$7.1M
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care SettingsR01AG069762 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GERSHON, RICHARD, NOWINSKI, CINDY J. · 2020 to 2025
$6.4M
Development and Validation of a Telehealth Strategy for Routine Detection of Cognitive Impairment in Primary Care: The MyCog Mobile AssessmentR01AG074245 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NOWINSKI, CINDY J., WOLF, MICHAEL S · 2021 to 2025
$3.8M
Use of Behavioral Economics in Repeat SARS-CoV-2 Antibody Testing in Disadvantaged CommunitiesR33AG057395 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DOCTOR, JASON N., SULLIVAN, MARK D · 2019 to 2021
$3.3M
Reducing High Risk Polypharmacy Using Behavioral Economics through Electronic Health RecordsR01AG070054 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERSELL, STEPHEN · 2022 to 2025
$1.9M
Implementing Prevention of Venous Thromboembolism for Ambulatory Patients with Cancer (PREVenT-APC)K23HL157758 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Karlyn Martin · 2022 to 2026
$831k
AHRQ HHS R01 HS026506AHRQ HHS R01 HS028127NHLBI NIH HHS K23 HL157758NIA NIH HHS P30 AG024968NIA NIH HHS P30 AG059988NIA NIH HHS R01 AG069762NIA NIH HHS R01 AG070054NIA NIH HHS R01 AG074245NIA NIH HHS R33 AG057395
6 · The paper itself

Abstract

Background: Evidenced-based interventions have been developed to prevent venous thromboembolism (VTE) in ambulatory patients with cancer, including VTE-risk assessment for all patients and targeted primary thromboprophylaxis for high-risk patients. Despite supportive evidence and recommendations, oncologists rarely assess VTE risk or provide primary prophylaxis. Our previous work identified barriers and facilitators to using VTE prevention interventions in oncology practice. Objectives: To identify potential strategies that address the identified barriers and leverage facilitators to achieve successful implementation of evidence-based interventions for VTE prevention in oncology practice. Methods: We used the Implementation Research Logic Model, an implementation science framework, to map the relationships among barriers and facilitators, feasible and effective implementation strategies, and implementation and clinical outcomes that will be used to evaluate the implementation strategies. Results: We identified 12 discrete implementation strategies (eg, conducting clinician education and training and staged implementation scale-up) that address barriers and leverage facilitators through their mechanisms of action (eg, increased clinician awareness of evidence and targeting the highest effectiveness). We identified key implementation (eg, penetration, adoption, acceptability, fidelity, appropriateness, and sustainability), system (eg, integration of VTE-risk assessment into clinical workflow), and clinical (eg, lower VTE rates) outcomes targeted by the selected strategies. Conclusion: Using the Implementation Research Logic Model framework and building on our knowledge of barriers and facilitators, we identified implementation strategies and important outcomes to evaluate these strategies. We will use these results to test and measure the strategies to improve the uptake of evidence-based recommendations for VTE prevention in oncology practice.

Indexed as

evidence-based practiceimplementation scienceneoplasmsrisk assessmentvenous thromboembolism

Identifiers

PMID37822563
PMCPMC10562910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.