Evidence map›Paper›PMID 37822485›Full record

ArticleClinical case reports2023

Paroxysmal nocturnal hemoglobinuria in a patient post COVID-19 virus infection: A case report with literature review.

Mohammed Albalawi, Turki Alwasaidi, Mohammed Almohammadi, Ashraf Ahmad Alzarief, Ghaleb Elyamany

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mohammed AlbalawiDepartment of Internal Medicine, College of Medicine Taibah University Madinah Saudi Arabia.ORCID https://orcid.org/0000-0001-6884-3221
Turki AlwasaidiDepartment of Internal Medicine, College of Medicine Taibah University Madinah Saudi Arabia.
Mohammed AlmohammadiKing Abdullah International Medical Research Center King Saud bin Abdulaziz University for Health Sciences, Pathology and Laboratory Medicine, King Abdulaziz Medical City Jeddah Saudi Arabia.
Ashraf Ahmad AlzariefDepartment of Neurosurgery Cairo University Cairo Egypt.
Ghaleb ElyamanyCentral Military Laboratory and Blood Bank Prince Sultan Military Medical City Riyadh Saudi Arabia.ORCID https://orcid.org/0000-0002-6334-4500
Taibah University · SACairo University · EGKing Saud bin Abdulaziz University for Health Sciences · SARiyadh Armed Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID 19 is a serious infection that originated in Wuhan, China and has resulted in worldwide morbidity and mortality. It continues to be a major health concern in 2022, being associated with multiorgan failure. Although the pathophysiology of the disease and its complications are not well understood, it is believed that a cytokine storm, triggered by complement activation may be responsible for the severity and complications of the disease. As of now, there is no definitive treatment available. Hematological changes associated with COVID-19 include lymphopenia, anemia, thrombocytopenia, disseminated intravascular coagulopathy, and thrombosis. Paroxysmal nocturnal hemoglobinuria (PNH), on the other hand, is an acquired clonal hematopoietic stem cell disorder that occurs due to an acquired PIG-A mutation affecting the hematopoietic stem cells. Interestingly, PNH exhibits some clinical and laboratory manifestations like those seen in COVID-19. In this report, we present a rare case of PNH that developed following a COVID-19 infection.

Indexed as

ComplementsCOVID‐19PNH

Identifiers

PMID37822485
PMCPMC10562656
OpenAlexW4387499285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.