ArticleFrontiers in medicine2023
Diagnostic accuracy of perfusion-weighted phase-resolved functional lung magnetic resonance imaging in patients with chronic pulmonary embolism.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Diagnostic Performance of Magnetic Resonance Imaging in Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review.Journal of medical imaging and radiation oncology · 2026Pooled it
- Characterizing chronic obstructive pulmonary disease using quantitative MRI biomarkers.The British journal of radiology · 2026Review
- Characteristics of pulmonary perfusion and ventilation in healthy adults: a prospective observational study with phase-resolved functional lung magnetic resonance imaging.BMC medical imaging · 2026Observational
- Phase-resolved functional lung magnetic resonance imaging for evaluation of lung perfusion and ventilation in fibrosing interstitial lung diseases.Insights into imaging · 2026Article
- Rapid Free-Breathing and Automated 2D Shimming of the Lung at 3T.Magnetic resonance in medicine · 2026Article
- Evaluation of pulmonary perfusion and ventilation in suspected chronic thromboembolic pulmonary hypertension via phase-resolved functional lung magnetic resonance imaging: correlations with hemodynamics and cardiopulmonary function.Quantitative imaging in medicine and surgery · 2025Article
- Enhanced Diagnostic Accuracy of Pulmonary Embolism: Integrating Low-Dose CT with V/Q SPECT.Tomography (Ann Arbor, Mich.) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to evaluate the diagnostic performance of perfusion-weighted phase-resolved functional lung (PW-PREFUL) magnetic resonance imaging (MRI) in patients with chronic pulmonary embolism (CPE). Materials and methods: This study included 86 patients with suspected chronic thromboembolic pulmonary hypertension (CTEPH), who underwent PREFUL MRI and ventilation/perfusion (V/Q) single-photon emission computed tomography/computed tomography (SPECT/CT). PREFUL MRI was performed at 1.5 T using a balanced steady-state free precession sequence during free breathing. Color-coded PW images and quantitative parameters were obtained by postprocessing. Meanwhile, V/Q SPECT/CT imaging was performed as a reference standard. Hypoperfused areas in the lungs were scored for each lobe and segment using V/Q SPECT/CT images and PW-PREFUL MR images, respectively. Normalized perfusion (Q Results: Of the 86 enrolled patients, 77 met the inclusion criteria (36 diagnosed with CPE using V/Q SPECT/CT and 41 diagnosed with non-CPE etiology). For the PW-PREFUL MRI, the sensitivity, specificity, accuracy, and positive and negative predictive values for the diagnosis of CPE were 97, 95, 96, 95, and 98% at the patient level; 91, 94, 93, 91, and 94% at the lobe level, and 85, 94, 92, 88, and 94% at the segment level, respectively. The detection of segmental and subsegmental hypoperfusion using PW-PREFUL MRI revealed a moderate agreement with V/Q SPECT/CT ( Conclusion: PREFUL MRI could be an alternative test to detect CPE without requiring breath-hold, contrast agents, or ionizing radiation.
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