Evidence map›Paper›PMID 37822452›Full record

ArticleMaterials today. Bio2023

Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was beneficial for long-term treatment of osteoarthritis.

Zhaowei Yin, Chaoren Qin, Shaowei Pan, Chen Shi, Guanfu Wu, Yan Feng, Jing Zhang, Ziyi Yu, Bin Liang, Jianchao Gui

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 48 citations in OpenAlex.

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  5. [Research progress of infrapatellar fat pad derived mesenchymal stem cells in treatment of osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhaowei YinDepartment of Orthopaedics, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Chaoren QinSports Medicine and Joint Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Shaowei PanDepartment of Orthopaedics, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Chen ShiDepartment of Orthopaedics, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Guanfu WuState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, PR China.
Yan FengSports Medicine and Joint Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Jing ZhangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, PR China.
Ziyi YuState Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, 30 Puzhu South Road, Nanjing 211816, PR China.
Bin LiangDepartment of Orthopaedics, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Jianchao GuiSports Medicine and Joint Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Nanjing Medical University · CNNanjing Tech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes (Exos) secreted by adipose-derived stem cells (ADSCs) have shown potential in alleviating osteoarthritis (OA). Previous studies indicated that infrapatellar fat pad (IPFP) derived stem cells (IPFSCs) may be more suitable for the treatment of OA than subcutaneous adipose tissue (ScAT) derived stem cells (ScASCs). However, it remains unclear which type of Exos offers superior therapeutic benefit for OA. This study first compared the differences between Exos derived from IPFP stem cells (Exos

Indexed as

ExosomesHydrogelMesenchymal stem cellsMicrofluidicsMicroRNAOsteoarthritis

Identifiers

PMID37822452
PMCPMC10562164
OpenAlexW4387082198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.