Evidence map›Paper›PMID 37821994›Full record

Trial reportTrials2023

Is a preoperative multidisciplinary team meeting (cost)effective to improve outcome for high-risk adult patients undergoing noncardiac surgery: the PREPARATION study-a multicenter stepped-wedge cluster randomized trial.

Jacqueline E M Vernooij, Romijn M Boerlage, Carine J M Doggen, Benedikt Preckel, Carmen D Dirksen, Barbara L van Leeuwen, Rutger J Spruit, Suzanne Festen, Hanneke van der Wal-Huisman, Jean P van Basten and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05703230 (Is a Preoperative Multidisciplinary Team Meeting), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05703230 naactive not recruitingnot on this map

Is a Preoperative Multidisciplinary Team Meeting (Cost) Effective in Optimizing Noncardiac Surgical Patient Management: The PREPARATION Study

TypeinterventionalSponsorRijnstate HospitalRan2022 to 2027Enrolled1,200ConditionsInterdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, OperativeArmsStructured preoperative multidisciplinary team meeting
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. [Clinical application of multidisciplinary team in the diagnosis and treatment of chronic refractory wounds].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Jacqueline E M VernooijDepartment of Anesthesiology, Rijnstate Hospital, Arnhem, The Netherlands. jvernooij@rijnstate.nl.ORCID http://orcid.org/0000-0003-3368-3111
Romijn M BoerlageDepartment of Anesthesiology, Rijnstate Hospital, Arnhem, The Netherlands.
Carine J M DoggenDepartment of Health Technology and Services Research, Technical Medical Centre, University of Twente, Enschedé, The Netherlands.
Benedikt PreckelDepartment of Anesthesiology, Amsterdam UMC Location AMC, Amsterdam Public Health, Quality of Care, Amsterdam Cardiovascular Science, Diabetes & Metabolism, Amsterdam, The Netherlands.
Carmen D DirksenCare and Public Health Research Institute, Maastricht University Medical Center, Maastricht, The Netherlands.
Barbara L van LeeuwenDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Rutger J SpruitDepartment of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Suzanne FestenUniversity Center for Geriatric Medicine, University Medical Center Groningen, Groningen, The Netherlands.
Hanneke van der Wal-HuismanDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Jean P van BastenDepartment of Urology, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Cor J KalkmanDepartment of Anesthesiology, University Medical Centre Utrecht, Utrecht, The Netherlands.
Nick J KoningDepartment of Anesthesiology, Rijnstate Hospital, Arnhem, The Netherlands.
PREPARATION study investigators
University Medical Center Groningen · NLUniversity Medical Center Utrecht · NLAmsterdam University Medical Centers · NLRijnstate Hospital · NLCanisius-Wilhelmina Ziekenhuis · NLMaastricht University · NL

Funding

ZonMw 10330032010003
6 · The paper itself

Abstract

backgroundAs a result of increased life expectancy and improved care for patients suffering from chronic disease, the number of patients with multimorbidity requiring surgical intervention is increasing. For complex surgical patients, it is essential to balance the potential benefits of surgical treatment against the risk of permanent loss of functional capacity and quality of life due to complications. European and US guidelines on perioperative care recommend preoperative multidisciplinary team (MDT) discussions for high-risk noncardiac surgical patients. However, the evidence underlying benefits from preoperative MDT meetings with all relevant perioperative specialties present is limited. The current study aims to investigate the effect of implementation of preoperative MDT discussions for high-risk patients undergoing noncardiac surgery on serious adverse events. METHODS/

designPREPARATION is a stepped-wedge cluster randomized trial in 14 Dutch hospitals without currently established preoperative MDT meeting. The intervention, preoperative MDT meetings, will be implemented sequentially with seven blocks of 2 hospitals switching from control (preoperative screening as usual) to the intervention every 3 months. Each hospital will be randomized to one of seven blocks. We aim to include 1200 patients. The primary outcome is the incidence of serious adverse events at 6 months. Secondary outcomes include (cost)effectiveness, functional outcome, and quality of life for up to 12 months. DISCUSSION: PREPARATION is the first study to assess the effectiveness of a preoperative MDT meeting for high-risk noncardiac surgical patients in the presence of an anesthesiologist. If the results suggest that preoperative MDT discussions for high-risk patients are (cost)-effective, the current study facilitates implementation of preoperative MDT meetings in clinical practice.

trial registrationClinicalTrials.gov NCT05703230. Registered on 11/09/2022.

Indexed as

MedicineQuality of LifeAdultHospitalsHumansPatient Care TeamPerioperative CareComplicationsCost-effectivenessCostsFrailtyHealth technology assessmentHigh-riskMortalityPatient’s preferencesPreoperative multidisciplinary teamQuality of lifeRisk toolsSerious adverse eventsStepped-wedge randomized cluster design

Identifiers

PMID37821994
PMCPMC10568883
OpenAlexW4387527158

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.