Evidence map›Paper›PMID 37821985›Full record

SynthesisHealth and quality of life outcomes2023

Impact of interventions on the quality of life of cancer patients: a systematic review and meta-analysis of longitudinal research.

Long Bao Nguyen, Linh Gia Vu, Thanh Thien Le, Xuan Thanh Nguyen, Nam Gia Dao, Duy Cao Nguyen, Trang Huyen Thi Dang, Thuc Minh Thi Vu, Laurent Boyer, Guillaume Fond and 5 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Health and quality of life outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Symptoms experienced during the first 4 months of chemotherapy administration: a longitudinal cohort study in an Australian cancer treatment unit.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Wellbeing status and priority concerns of patients with advanced renal cell carcinoma: results of the EONS PROMs project international online survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Long Bao NguyenInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, 100000, Vietnam.
Linh Gia VuInstitute for Global Health Innovations, Duy Tan University, 550000, Da Nang, Vietnam.
Thanh Thien LeDepartment of Biomedical Engineering, Tufts University, 200 College Avenue, Medford, MA, 02155, USA.
Xuan Thanh NguyenHue Central General Hospital, Hue, 52000, Vietnam.
Nam Gia DaoInstitute for Global Health Innovations, Duy Tan University, 550000, Da Nang, Vietnam.
Duy Cao NguyenInstitute for Global Health Innovations, Duy Tan University, 550000, Da Nang, Vietnam. nguyencaoduy@duytan.edu.vn.
Trang Huyen Thi DangInstitute of Health Economics and Technology (iHEAT), Hanoi, Vietnam.
Thuc Minh Thi VuInstitute of Health Economics and Technology (iHEAT), Hanoi, Vietnam.
Laurent BoyerResearch Centre on Health Services and Quality of Life, Aix Marseille University, 27, boulevard Jean-Moulin, CEReSS, Marseille cedex 05, 3279, 13385, France.
Guillaume FondResearch Centre on Health Services and Quality of Life, Aix Marseille University, 27, boulevard Jean-Moulin, CEReSS, Marseille cedex 05, 3279, 13385, France.
Pascal AuquierResearch Centre on Health Services and Quality of Life, Aix Marseille University, 27, boulevard Jean-Moulin, CEReSS, Marseille cedex 05, 3279, 13385, France.
Carl A LatkinBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA.
Melvyn W B ZhangLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
Roger C M HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.
Cyrus S H HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.

Funding

NUS Department of Psychological Medicine R-177-000-100-001/R-177-000-003-001/ R177000702733NUS iHeathtech Other Operating Expenses R-722-000-004-731
6 · The paper itself

Abstract

The impact of cancer interventions has been conducted in several research due to the significant burden of this non-communicable disease. The interventions that played an important role in the improvement of the patient's quality of life (QoL) and health-related quality of life (HRQL) can be classified into two main groups: pharmaceutical and non-pharmacological methods. However, studies so far often analyze a specific group of interventions for specific types of cancer. Thus, in this systematic review and meta-analysis, we synthesized the overall impact of cancer interventions on patients' quality of life in several cancers.In this research, we followed the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) to search the longitudinal original research on the Web of Science (WOS) database. After that, the Newcastle-Ottawa Scale (NOS) and Jadad Scale were used to assess the quality of non-randomized control trials and randomized control trials, respectively. Then, the characteristics of the included studies were described in the six main fields table and the random effect model with robust estimation was applied to analyze the impact of interventions on the health utility of patients.From the database, 122 longitudinal original research were included in the meta-regression, with most of them having high or fair quality. The European Organization for the research and treatment of cancer scale for quality of life (EORTC-QLQ) was the most used health utility measurement at 65.15%. In the adjusted effect models, the Visual Analogue Scale (VAS) had significant statistics in all models when we compared it with the EQ-5D Scale (p < 0.05) and several types of cancer such as breast, lung, and prostate cancer had significant statistics when comparing with hematological cancer in the model types of cancer (p < 0.01). Moreover, radiotherapy, screening, and a combination of chemotherapy and best supportive care also had significant statistics (p < 0.01) in the model of interventions when compared with radiotherapy applied only. Our research can suggest a vital combination of both pharmaceutical and non-pharmacological interventions to improve the quality of life of some common types of cancer patients.

Indexed as

NeoplasmsQuality of LifeFemaleHumansMalePharmaceutical PreparationsPharmaceutical PreparationsCancerHRQLInterventionsQuality of life

Identifiers

PMID37821985
PMCPMC10566122

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.