Evidence map›Paper›PMID 37821742›Full record

ArticleAngewandte Chemie (International ed. in English)2023

Expanding the Range of Bioorthogonal Tags for Multiplex Stimulated Raman Scattering Microscopy.

Neville Murphy, William J Tipping, Henry J Braddick, Liam T Wilson, Nicholas C O Tomkinson, Karen Faulds, Duncan Graham, Pau Farràs

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Neville MurphySchool of Biological and Chemical Sciences, University of Galway, Galway, H91CF50, Ireland.
William J TippingCentre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, G1 1RD, United Kingdom.ORCID 0000-0003-4273-2691
Henry J BraddickDepartment of Pure and Applied Chemistry, University of Strathclyde, Glasgow, G1 1XL, United Kingdom.
Liam T WilsonDepartment of Pure and Applied Chemistry, University of Strathclyde, Glasgow, G1 1XL, United Kingdom.
Nicholas C O TomkinsonDepartment of Pure and Applied Chemistry, University of Strathclyde, Glasgow, G1 1XL, United Kingdom.
Karen FauldsCentre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, G1 1RD, United Kingdom.
Duncan GrahamCentre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, Glasgow, G1 1RD, United Kingdom.ORCID 0000-0002-6079-2105
Pau FarràsSchool of Biological and Chemical Sciences, University of Galway, Galway, H91CF50, Ireland.
University of Strathclyde · GBOllscoil na Gaillimhe – University of Galway · IE

Funding

Science Foundation Ireland
6 · The paper itself

Abstract

Multiplex optical detection in live cells is challenging due to overlapping signals and poor signal-to-noise associated with some chemical reporters. To address this, the application of spectral phasor analysis to stimulated Raman scattering (SRS) microscopy for unmixing three bioorthogonal Raman probes within cells is reported. Triplex detection of a metallacarborane using the B-H stretch at 2480-2650 cm

Indexed as

Fatty AcidsNonlinear Optical MicroscopyMicroscopySpectrum Analysis, RamanFatty AcidsBioorthogonal LabelingImaging ProbesRaman MicroscopySpectral Phasor AnalysisStimulated Raman Scattering

Identifiers

PMID37821742
PMCPMC10952743
OpenAlexW4387564166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.