ArticleNature2023
Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Erratum issued Registry-linked trialAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06523582 (Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients), which is not on this map. Cited by 79 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.Nature communications · 2025Pooled it
- Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.Nature communications · 2025Pooled it
- Article
- Article
- Article
- Whole genome sequencing of 1427 Mexican individuals from the oriGen cohort.Nature communications · 2026Article
- Article
- Adiposity and infection-related mortality: Mendelian randomization study of 126 000 Mexican adults.International journal of epidemiology · 2026Article
- Validation of the European SCORE2 algorithm in one European and one Latin-American cohort studies with contrasting populations.European heart journal. Quality of care & clinical outcomes · 2026Observational
- Article
- Multitrait analysis of genome-wide association studies expands eosinophilic esophagitis genetic susceptibility and polygenic risk scores.The Journal of allergy and clinical immunology · 2026Article
- Extending genome-wide association studies to admixed cohorts with high degrees of relatedness.Nature genetics · 2026Article
- Prevalence of TPMT and NUDT15 diplotypes in Mexican children with B-cell acute lymphoblastic leukemia.Pharmacogenetics and genomics · 2026Article
- Type 2 diabetes genetics in 125,000 admixed adults from Mexico City.medRxiv : the preprint server for health sciences · 2026Article
- Rare protein-coding variation and the genetic architecture of height in >1.4 million individuals.medRxiv : the preprint server for health sciences · 2026Article
- A novel splice site variant in DEGS1 leads to aberrant splicing and loss of DEGS1 enzyme activity, a VUS resolved.Human genetics · 2026Article
- Ancestral diversity in complex disease genetics: from discovery to translation.Nature reviews. Genetics · 2026Review
- Article
- Association study uncovers obesity-linked variants in mobile elements as potential regulators of gene expression.iScience · 2026Article
- A reference panel for linkage disequilibrium and genotype imputation using whole-genome sequencing data from 2,680 participants across India.HGG advances · 2026Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
49 authors.
Andrey Ziyatdinov *Regeneron Genetics Center, Tarrytown, NY, USA.
Jason Torres *Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. jason.torres@ndph.ox.ac.uk.ORCID 0000-0002-7537-7035
Jesús Alegre-Díaz *Experimental Research Unit from the Faculty of Medicine (UIME), National Autonomous University of Mexico (UNAM), Mexico City, Mexico.ORCID 0000-0001-9390-3871
Joshua BackmanRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0001-7262-0880
Joelle MbatchouRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0002-2245-3743
Michael TurnerClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0002-0351-4053
Sheila M GaynorRegeneron Genetics Center, Tarrytown, NY, USA.
Tyler JosephRegeneron Genetics Center, Tarrytown, NY, USA.
Yuxin ZouRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0001-9816-5847
Daren LiuRegeneron Genetics Center, Tarrytown, NY, USA.
Rachel WadeClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0001-9826-6322
Jeffrey StaplesRegeneron Genetics Center, Tarrytown, NY, USA.
Razvan PaneaRegeneron Genetics Center, Tarrytown, NY, USA.
Alex PopovRegeneron Genetics Center, Tarrytown, NY, USA.
Xiaodong BaiRegeneron Genetics Center, Tarrytown, NY, USA.
Suganthi BalasubramanianRegeneron Genetics Center, Tarrytown, NY, USA.
Lukas HabeggerRegeneron Genetics Center, Tarrytown, NY, USA.
Rouel LancheRegeneron Genetics Center, Tarrytown, NY, USA.
Alex LopezRegeneron Genetics Center, Tarrytown, NY, USA.
Evan MaxwellRegeneron Genetics Center, Tarrytown, NY, USA.
Marcus JonesRegeneron Genetics Center, Tarrytown, NY, USA.
Humberto García-OrtizInstituto Nacional de Medicina Genómica, Tlalpan, Mexico City, Mexico.ORCID 0000-0002-0453-980X
Raul Ramirez-ReyesExperimental Research Unit from the Faculty of Medicine (UIME), National Autonomous University of Mexico (UNAM), Mexico City, Mexico.ORCID 0000-0001-9763-324X
Rogelio Santacruz-BenítezExperimental Research Unit from the Faculty of Medicine (UIME), National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
Abhishek NagCentre for Genomics Research, Discovery Sciences, Research and Development Biopharmaceuticals, AstraZeneca, Cambridge, UK.
Katherine R SmithCentre for Genomics Research, Discovery Sciences, Research and Development Biopharmaceuticals, AstraZeneca, Cambridge, UK.ORCID 0000-0002-0329-5938
Amy DamaskRegeneron Genetics Center, Tarrytown, NY, USA.
Nan LinRegeneron Genetics Center, Tarrytown, NY, USA.
Charles PauldingRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0002-7918-3561
Mark ReppellAbbVie, North Chicago, IL, USA.ORCID 0000-0001-7992-4537
Sebastian ZöllnerDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-7362-156X
Eric JorgensonRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0002-5829-8191
William SalernoRegeneron Genetics Center, Tarrytown, NY, USA.
Slavé PetrovskiCentre for Genomics Research, Discovery Sciences, Research and Development Biopharmaceuticals, AstraZeneca, Cambridge, UK.ORCID 0000-0002-1527-961X
John OvertonRegeneron Genetics Center, Tarrytown, NY, USA.
Jeffrey ReidRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0001-8645-4713
Timothy A ThorntonRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0001-7071-2642
Gonçalo AbecasisRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0003-1509-1825
Jaime BerumenExperimental Research Unit from the Faculty of Medicine (UIME), National Autonomous University of Mexico (UNAM), Mexico City, Mexico.ORCID 0000-0001-6707-3317
Lorena Orozco-OrozcoInstituto Nacional de Medicina Genómica, Tlalpan, Mexico City, Mexico.ORCID 0000-0002-5801-9180
Rory CollinsClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Regeneron Genetics Center
Mexico City Prospective Study
Aris BarasRegeneron Genetics Center, Tarrytown, NY, USA.ORCID 0000-0002-6830-3396
Michael R HillClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Jonathan R EmbersonClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0001-7792-9422
Jonathan MarchiniRegeneron Genetics Center, Tarrytown, NY, USA. jonathan.marchini@regeneron.com.ORCID 0000-0003-0610-8322
Pablo Kuri-MoralesInstituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, Mexico.ORCID 0000-0002-0704-9507
Roberto Tapia-ConyerFaculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico. tapiaconyer@gmail.com.ORCID 0000-0003-3814-2904
Funding
Medical Research Council MC_UU_00017/2Wellcome Trust
Abstract
The Mexico City Prospective Study is a prospective cohort of more than 150,000 adults recruited two decades ago from the urban districts of Coyoacán and Iztapalapa in Mexico City
Indexed as
Exome SequencingGenome, HumanGenotypeHispanic or LatinoAdultAfricaAmericasEuropeGene FrequencyGenetics, PopulationGenotyping TechniquesHomozygoteHumansLoss of Function MutationMexicoProspective Studies
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
NCT06523582ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.