Evidence map›Paper›PMID 37821649›Full record

ArticleWorld journal of surgery2023

A Prospective, Observational Cost Comparison of Laparoscopic and Open Appendicectomy in Three Tertiary Hospitals in Nigeria.

Adewale Adisa, Mwayi Kachapila, Christopher Ekwunife, Felix Alakaloko, Balogun Olanrewaju, Bryar Kadir, Dmitri Nepogodiev, Adewale Aderounmu, Innocent Igwilo, Omar Omar and 5 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in World journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Adewale AdisaDepartment of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, 220005, Nigeria. ao.adisa@oauife.edu.ng.ORCID 0000-0003-1927-3992
Mwayi KachapilaNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Christopher EkwunifeDepartment of Surgery, Federal Medical Center, Owerri, Nigeria.
Felix AlakalokoDepartment of Surgery, Lagos University Teaching Hospital, Lagos, Nigeria.
Balogun OlanrewajuDepartment of Surgery, Lagos University Teaching Hospital, Lagos, Nigeria.
Bryar KadirNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Dmitri NepogodievNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Adewale AderounmuDepartment of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, 220005, Nigeria.
Innocent IgwiloDepartment of Surgery, Federal Medical Center, Owerri, Nigeria.
Omar OmarNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Raymond OppongHealth Economics Unit, University of Birmingham, Birmingham, United Kingdom.
Joana SimoesNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Aneel BhanguNIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, United Kingdom.
Adesoji AdemuyiwaDepartment of Surgery, Federal Medical Center, Owerri, Nigeria.
NIHR Global Health Research Unit on Global Surgery
Federal Medical Centre · NGNIHR Birmingham Biomedical Research Centre · GBBirmingham City University · GBLagos University Teaching Hospital · NGObafemi Awolowo University Teaching Hospitals Complex · NG

Funding

Birmingham Biomedical Research Centre Grant (NIHR16.136.79)
6 · The paper itself

Abstract

backgroundThe clinical benefits of laparoscopic appendicectomy are well recognized over open appendicectomy. However, laparoscopic procedures are not frequently conducted in many low-and middle-income countries (LMICs) for several reasons, including perceived higher costs. The aim of this study was to assess the feasibility and cost of laparoscopic appendicectomy compared to open appendicectomy in Nigeria.

methodsA multicenter, prospective, cohort study among patients undergoing appendicectomy was conducted at three tertiary hospitals in Nigeria. Data were collected from October 2020 to February 2022 and analyses compared the average healthcare costs at 30 days after surgery. Quantile regression was conducted to identify variables that had an impact on the costs, reported in Nigerian Naira (Naira) and US dollars ($), with standard deviations (SD).

findingsThis study included 105 patients, of which 39 had laparoscopic appendicectomy and 66 had open appendicectomy. The average healthcare cost of laparoscopic appendicectomy (147,562 Naira (SD: 97,130) or $355 (SD: 234)) was higher than open appendicectomy (113,556 Naira (SD: 88,559) or $273 (SD: 213)). The average time for return to work was shorter with laparoscopic than open appendicectomy (mean: 8 days vs. 14 days). At the average daily income of $5.06, laparoscopic appendicectomy was associated with 9778 Naira or $24 cost savings in return to work. Further, 5.1% of laparoscopic appendicectomy patients had surgical site infections compared to 22.7% for open appendicectomy. Regression analysis results showed that laparoscopic appendicectomy was associated with $14 higher costs than open appendicectomy, albeit non-significant (p = 0.53).

interpretationDespite selection bias in this real-world study, laparoscopic appendicectomy was associated with a slightly higher overall cost, a lower societal cost, a lower infection rate, and a faster return to work, compared to open appendicectomy. It is technically and financially feasible, and its provision in Nigeria should be expanded.

Indexed as

AppendicitisLaparoscopyAppendectomyCohort StudiesHealth Care CostsHumansLength of StayNigeriaProspective StudiesTertiary Care Centers

Identifiers

PMID37821649
PMCPMC10694127
OpenAlexW4387523543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.