ArticleScientific reports2023
Correlation of procalcitonin and c-reactive protein levels with pathogen distribution and infection localization in urinary tract infections.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Correlation of CT-Derived Quantitative Image Features and Inflammatory Laboratory Markers with Length of Hospital Stay in Patients with Pyelonephritis.Diagnostics (Basel, Switzerland) · 2026Article
- Correlation of Age and Laboratory Parameters with Urine Flow Cytometry and Culture Results in Patients with Urinary Tract Infections.Infectious disease reports · 2026Article
- Procalcitonin for Predicting Sepsis in Infants in the Emergency Department: A Retrospective Study.Pediatric health, medicine and therapeutics · 2026Article
- Clinical efficacy of combined detection of serum procalcitonin and C-reactive protein in early differential diagnosis of bacterial and viral pneumonia and analysis of related inflammatory response mechanisms.Biomarkers in medicine · 2025Article
- A personalized prediction model for distinguishing between asymptomatic bacteriuria and symptomatic urinary tract infections in patients with type 2 diabetes mellitus using machine learning.Frontiers in endocrinology · 2025Article
- Analysis of pathogen distribution and serum procalcitonin level alterations in patients with type 2 diabetes mellitus complicated by urinary tract infections.Frontiers in endocrinology · 2025Article
- Prediction of Bacterial Etiology in Pediatric Patients with Acute Epididymitis: A Comparison of C-Reactive Protein and Urinalysis in Terms of Diagnostic Accuracy.Biomedicines · 2024Article
- Random forest differentiation of Escherichia coli in elderly sepsis using biomarkers and infectious sites.Scientific reports · 2024Article
- Epidemiological insights into seasonal, sex‑specific and age‑related distribution of bacterial pathogens in urinary tract infections.Experimental and therapeutic medicine · 2024Article
- The Diagnostic Accuracy of Procalcitonin, Soluble Urokinase-Type Plasminogen Activator Receptors, and C-Reactive Protein in Diagnosing Urinary Tract Infections in the Emergency Department-A Diagnostic Accuracy Study.Journal of clinical medicine · 2024Article
- Transient Ischaemic Attack in a Patient With Conn Syndrome: A Case Report and Literature Review on the Importance of Identifying Secondary Hypertension.In vivo (Athens, Greece)Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aimed to explore the relationships between infection localization, bacterial species, and procalcitonin (PCT) and C-reactive protein (CRP) levels in urinary tract infections (UTIs). A retrospective study included 314 UTI hospitalized patients divided into two groups (268 with lower UTI, 46 with upper UTI) in a tertiary care hospital. PCT and CRP were performed. Bacterial isolates were identified using standard microbiological techniques, and statistical analyses were performed to assess associations between infection localization, bacterial species, PCT, and CRP levels. Age and gender showed no significant differences between the lower and upper UTIs. Escherichia coli dominated as the leading UTI pathogen. A positive correlation (r = 0.646, P < 0.001) between PCT and CRP levels was found. The subgroup with ureteritis in the upper UTI category exhibited the highest PCT and CRP levels. PCT and CRP exhibited favorable diagnostic potential in predicting upper UTIs, with AUCs of 0.644 and 0.629, respectively. The optimal cutoff values were 0.21 ng/mL for PCT and 60.77 mg/L for CRP. Sensitivities were 69.03% and 77.99%, while specificities were 56.52% and 47.83%, respectively. E. coli emerged as the predominant bacterium in UTIs. PCT and CRP demonstrated moderate diagnostic efficacy in distinguishing between upper and lower UTIs. Notably, PCT and CRP exhibited enhanced utility in identifying ureteritis.
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