Evidence map›Paper›PMID 37821124›Full record

ArticleBMJ paediatrics open2023

Evaluation of procedural pain for neonates in a neonatal intensive care unit: a single-centre study.

Feixiang Luo, Huaiyu Zhu, Lingli Mei, Qi Shu, Xiaoying Cheng, Xiaofei Chen, Yisheng Zhao, Shuohui Chen, Yun Pan

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in BMJ paediatrics open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06885437 (Neonatal Intensive Care Nurses' Assessment of Preterm Infants' Pain and Sedation), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06885437 completednot on this map

Neonatal Intensive Care Nurses' Assessment of Preterm Infants' Pain and Sedation: Inter-Rater Reliability

TypeobservationalSponsorAcibadem UniversityRan2023 to 2023Enrolled190ConditionsNurse Care CoordinationArmsPain and sedation assessment with the N-PASS scale by each nurse
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Neonatal Pain Management: Is There An Endocrinal Response?Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Feixiang Luo *Neonatal Intensive Care Unit, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.ORCID 0000-0001-8473-3022
Huaiyu Zhu *College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0001-6918-4088
Lingli MeiAdministration Department of Nosocomial Infection, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.ORCID 0000-0002-2582-6330
Qi ShuAdministration Department of Nosocomial Infection, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Xiaoying ChengQuality Improvement Office, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Xiaofei ChenGastroenterology Department, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Yisheng ZhaoCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-0763-3658
Shuohui ChenAdministration Department of Nosocomial Infection, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China chcsh2@zju.edu.cn panyun@zju.edu.cn.ORCID 0000-0002-1006-2964
Yun PanCollege of Information Science and Electronic Engineering, Zhejiang University, Hangzhou, Zhejiang, China chcsh2@zju.edu.cn panyun@zju.edu.cn.ORCID 0000-0002-9335-4291
Children's Hospital of Zhejiang University · CNZhejiang University · CNImprovement Service · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the procedural pain experienced by neonates in a neonatal intensive care unit (NICU) setting and determine the corresponding pain grades.

methodsTwo experienced nurses independently used the Neonatal Infant Pain Scale (NIPS) to evaluate the neonatal pain during procedures taking place in the tertiary NICU and two level-two neonatal care units in the Children's Hospital of Zhejiang University School of Medicine. The mean and distribution of NIPS pain scores and the corresponding pain grades of participants when experiencing clinical painful procedures were analysed.

resultsA total of 957 neonates exposed to 15 common clinical painful procedures were included in the study. The clinical painful procedures experienced by 957 participants could be divided into three groups: severe pain (NIPS score 5-7: peripheral intravenous cannulation, arterial catheterisation, arterial blood sampling, peripherally inserted central catheter placement and nasopharyngeal suctioning), mild to moderate pain (NIPS score 3-4: finger prick, intramuscular injection, adhesive removal, endotracheal intubation suctioning, heel prick, lumbar puncture and subcutaneous injection) and no pain to mild pain (NIPS score 0-2: gastric tube insertion, enema and intravenous injection).

conclusionsThe neonatal pain response to clinical procedures in NICU had certain pattern and preintervention drug analgesia could be taken for painful procedures with clustered high NIPS pain scores. Meanwhile, full coverage non-drug pain relief measures could be taken for procedures that are with scattered pain scores, and real-time pain evaluation should be provided to determine whether further drug analgesia is required.

Indexed as

Catheterization, PeripheralProcedural PainChildHumansInfantInfant, NewbornIntensive Care Units, NeonatalPainPain Managementneonatologynursing carepain

Identifiers

PMID37821124
PMCPMC10582867
OpenAlexW4387517678

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.