Evidence map›Paper›PMID 37820230›Full record

ArticleCadernos de saude publica2023

[Judicialization of cannabidiol-based products in Brazil: an analysis from 2019 to 2022].

Ronaldo Portela, Daniel Marques Mota, Paulo José Gonçalves Ferreira, Mariana Dias Lula, Bruno Barcala Reis, Helian Nunes de Oliveira, Cristina Mariano Ruas

Abstract readEnglish Abstract
In one paragraph

Article in Cadernos de saude publica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ronaldo PortelaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0002-6267-1278
Daniel Marques MotaAgência Nacional de Vigilância Sanitária, Brasília, Brasil.ORCID 0000-0003-4156-0138
Paulo José Gonçalves FerreiraAgência Nacional de Vigilância Sanitária, Brasília, Brasil.ORCID 0000-0001-5042-4213
Mariana Dias LulaFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0003-0760-4424
Bruno Barcala ReisDefensoria Pública do Estado de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0002-4836-671X
Helian Nunes de OliveiraFaculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0003-1635-5175
Cristina Mariano RuasFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0003-0275-8416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study analyzed the lawsuits of patients who requested cannabidiol (CBD)-based products from the Brazilian Unified National Health System during the period from 2019 to 2022, describing sociodemographic, clinical, and legal characteristics. This is a cross-sectional study composed of the evaluation of the technical notes issued by the Center for Technical Support of the Judiciary (NatJus), which supports judicial decisions. The data were obtained from the e-NatJus system, of the Brazilian Ministry of Justice, using web scraping techniques. Logistic regression was used to estimate odds ratios with 95% confidence intervals. We analyzed 1,115 technical notes of the CBD plaintiffs, of which 54.7% of the male patients, with a mean age of 18.4 years, mostly from the South Region of the country (38.8%), and 49.6% sought treatment for epilepsy. Regarding the actions with favorable opinions, 28.8% had no scientific evidence, 26.5% pleaded for products without registration with the Brazilian Health Regulatory Agency, and 25.3% of those that had registration were not in compliance with the therapeutic indication. Patients from the Northeast Region had a chance of a favorable opinion increased by 3.0 times and those diagnosed with epilepsy by 2.3. The expert opinions that supported the magistrates for the judicial decisions regarding the demands of patients for cannabidiol-based products in Brazil were mostly in accordance with scientific evidence, denoting the importance of NatJus in the qualification of access to medicinal products in the country.

Indexed as

CannabidiolEpilepsyAdolescentBrazilCross-Sectional StudiesHealth Services AccessibilityHumansMaleCannabidiol

Identifiers

PMID37820230
PMCPMC10566558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.