ArticleBlood advances2024
Maintenance therapy for early loss of B-cell aplasia after anti-CD19 CAR T-cell therapy.
Open access · goldAbstract read
In one paragraph
Article in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- CAR T-cell therapy in patients with acute lymphoblastic leukemia: a systematic review and meta-analysis.Bone marrow transplantation · 2026Pooled it
- Decade-long persistence of CD19 CAR T cells in B cell lymphomas.Nature medicine · 2026Trial
- Trial
- Consolidative allogeneic HCT vs. a watch-and-wait approach for B-cell acute lymphoblastic leukemia patients with early loss of B-cell aplasia after CAR T-cell therapy.Bone marrow transplantation · 2026Article
- Improved outcomes with TKI maintenance after brexucabtagene autoleucel in Philadelphia chromosome ALL.Blood advances · 2026Article
- The dilemma after chimeric antigen receptor T-cell therapy - to transplant or not?Haematologica · 2026Article
- Incorporating Immunotherapies into the Evolving Standard of Care for Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.Paediatric drugs · 2026Review
- B Cell Aplasia Following CAR T Cell Therapy: Incidence, Kinetics, Prognostic Implications, and Clinical Management.Cancers · 2026Review
- The evolving landscape of CAR T cell therapy in children and young adults with B cell acute lymphoblastic leukemia.Molecular therapy. Oncology · 2026Review
- A Literature Review of Immunotherapeutics in the Management of Adult B-Cell Acute Lymphoblastic Leukemia.Blood and lymphatic cancer : targets and therapy · 2026Review
- Maintenance after CAR T? Are we there yet? Reducing the risk of relapse after loss of anti-CD19 CAR T-cell persistence in ALL.Hematology. American Society of Hematology. Education Program · 2025Article
- CSF1R-CAR T cells induce CSF1R signaling and can promote target cell proliferation.Science signaling · 2025Article
- Harmonization on defining B-cell recovery post CD19-CAR T-cell therapy in B-cell acute lymphoblastic leukemia: An international consensus statement.HemaSphere · 2025Article
- The Struggle Between Chimeric Antigen Receptor T-Cell Therapy and Neurological Complications in Acute Lymphoblastic Leukemia Treatment.Current issues in molecular biology · 2025Review
- Novel humanized CD19-CAR-T (Now talicabtagene autoleucel, Tali-cel™) cells in relapsed/ refractory pediatric B-acute lymphoblastic leukemia- an open-label single-arm phase-I/Ib study.Blood cancer journal · 2025Article
- Dual-targeting CAR T cells for B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma.Blood advances · 2025Review
- How I treat postimmunotherapy relapsed B-ALL.Blood · 2025Review
- Effective MRD clearance and long-term survival with CD19 CAR-T in pediatric B-ALL patients with MRD positivity or chemotherapy intolerance.Frontiers in immunology · 2025Article
- Influence of CAR T-cell therapy associated complications.Frontiers in oncology · 2025Review
- Incidence of preexisting B-cell aplasia in B-ALL: implications for post-CAR T-cell monitoring.Blood advances · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 9 institutions in 3 countries.
Maria GabelliDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.ORCID 0000-0002-6226-9895
Macarena Oporto-EspuelasMolecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, United Kingdom.
Saskia BurridgeDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Jan ChuDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Susan FarishDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Emma HedgesDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Kirsty WareDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Lindsey WilliamsDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Lindsey YoungDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Rajesh AlajangiBristol Haematology and Oncology Centre, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Philip AncliffDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Jack BartramDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Denise BonneyDepartment of Bone Marrow Transplantation, Royal Manchester Children's Hospital, Manchester, United Kingdom.
Lenka ChencharaDivision of Pediatric Hematology Oncology, Sidra Medicine, Doha, Qatar.
Robert ChiesaDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Chiara CugnoDivision of Pediatric Hematology Oncology, Sidra Medicine, Doha, Qatar.ORCID 0000-0002-1664-3030
Katharine HodbyBristol Haematology and Oncology Centre, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom.
Katarzyna A JalowiecHaematology, University College London Hospital, London, United Kingdom.ORCID 0000-0003-3284-8308
Arina LazarevaDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Giovanna LucchiniDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Oana C Mirci-DanicarDepartment of Bone Marrow Transplantation, Royal Hospital for Children, Bristol, United Kingdom.
Khushnuma MullanfirozeDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Vesna PavasovicDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Anupama RaoDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Kanchan RaoDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Lynne RileyDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Sujith SamarasingheDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Geoff ShentonPaediatric Oncology and Haematology, Great North Children's Hospital, Newcastle-upon-Tyne, United Kingdom.
Juliana SilvaDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.
Ajay VoraDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.
Rachael HoughHaematology, University College London Hospital, London, United Kingdom.
Persis J AmroliaDepartment of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, United Kingdom.ORCID 0000-0003-0480-3911
Sara GhorashianDepartment of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom.ORCID 0000-0002-1555-2946
Great Ormond Street Hospital · GBQatar Airways (Qatar) · QAUniversity College Hospital · GBUniversity Hospitals Bristol NHS Foundation Trust · GBBristol Royal Hospital for Children · GBGreat North Children's Hospital · GBRoyal Manchester Children's Hospital · GBUniversity College London · GBUniversity of Padua · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
B-LymphocytesImmunotherapy, AdoptiveReceptors, Antigen, T-CellAntigens, CD19Receptors, Chimeric AntigenT-LymphocytesAntigens, CD19Receptors, Antigen, T-CellReceptors, Chimeric Antigen
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.