Evidence map›Paper›PMID 37819947›Full record

ArticlePloS one2023

Sex differences in a murine model of asthma are time and tissue compartment dependent.

Sergio E Chiarella, Lyda Cuervo-Pardo, Mackenzie E Coden, Brian M Jeong, Ton C Doan, Andrew R Connelly, Raul I Rodriguez, Ashley M Queener, Sergejs Berdnikovs

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Journal of pharmaceutical analysis · 2026
    Article
  2. Article
  3. Sex Differences in Lung Immunity.Immunological reviews · 2026
    Review
  4. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  5. Review
  6. Sex Differences in Lung B Cell Responses in a Murine Model of Asthma.International archives of allergy and immunology · 2026
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sergio E ChiarellaDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.ORCID 0000-0002-0445-4929
Lyda Cuervo-PardoUniversity of Florida, Gainesville, FL, United States of America.
Mackenzie E CodenDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Brian M JeongDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Ton C DoanDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Andrew R ConnellyDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Raul I RodriguezDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Ashley M QueenerDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Sergejs BerdnikovsDivision of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.ORCID 0000-0001-5186-3293
Northwestern University · USUniversity of Florida · US

Funding

Hormones in allergic diseaseR01AI127783 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BERDNIKOVS, SERGEJS · 2017 to 2021
$2.0M
Gender-specific effects of puberty on airway epithelial differentiation in asthmaK08AI141765 · NIAID · MAYO CLINIC ROCHESTER · PI CHIARELLA, SERGIO E · 2019 to 2023
$929k
Novel asthma pathogenesis genes in the mucosa of the human airwaysR21AI115055 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BERDNIKOVS, SERGEJS · 2015 to 2016
$425k
NIAID NIH HHS K08 AI141765NIAID NIH HHS R01 AI127783NIAID NIH HHS R21 AI115055
6 · The paper itself

Abstract

conclusionSexual dimorphism in lung inflammation is both time and tissue compartment dependent. Spatiotemporal variability in sex differences in a murine model of asthma must be accounted for when planning experiments to model the sex bias in allergic inflammation.

Indexed as

AsthmaPneumoniaAnimalsDisease Models, AnimalFemaleInflammationLungMaleMiceMice, Inbred BALB CSex Characteristics

Identifiers

PMID37819947
PMCPMC10566727
OpenAlexW4387541538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.