Evidence map›Paper›PMID 37819943›Full record

ArticlePloS one2023

The menstrual cycle and the COVID-19 pandemic.

Anita Mitra, Jan Y Verbakel, Lorraine S Kasaven, Menelaos Tzafetas, Karen Grewal, Benjamin Jones, Phillip R Bennett, Maria Kyrgiou, Srdjan Saso

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Implications of Dysnatremia and Endocrine Disturbances in COVID-19 Patients.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Anita MitraInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Jan Y VerbakelDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Lorraine S KasavenInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.ORCID 0000-0002-1752-5220
Menelaos TzafetasInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Karen GrewalInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Benjamin JonesInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Phillip R BennettInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Maria KyrgiouInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Srdjan SasoInstitute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Imperial College Healthcare NHS Trust · GBImperial College London · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of COVID-19 virus on menstrual cycles in unvaccinated women is limited.

objectiveTo investigate the prevalence of changes to menstrual cycle characteristics, hormonal symptoms and lifestyle changes prior to and during the COVID-19 pandemic.

methodsA retrospective online cross-sectional survey completed by social media users between July 2020 to October 2020. Participants were living in the United Kingdom (UK), premenopausal status and, or over 18 years of age. MAIN OUTCOME(S) AND MEASURES(S): The primary outcome was to assess changes to menstrual cycle characteristics during the pandemic following the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). Secondary outcomes included assessment of hormonal and lifestyle changes.

results15,611 social media users completed the survey. Of which, 75% of participants experienced a change in their menstrual cycle, with significantly greater proportions reporting irregular menstrual cycles (P<0·001), bleeding duration more than seven days (P<0·001), longer mean cycle length (P<0·001) and overall bleeding duration (P<0·001). Over half the participants reported worsening of premenstrual symptoms including low mood/depression, anxiety and irritability. When stratified according to COVID-19 infection, there was no significant difference in menstrual cycle changes.

conclusionThe COVID-19 pandemic resulted in considerable variation in menstrual cycle characteristics and hormonal symptoms. This appears to be related to societal and lifestyle changes resulting from the pandemic, rather than to the virus itself. We believe this may have an impact on the individual, as well as national economy, healthcare, and population levels, and therefore suggest this should be taken into consideration by governments, healthcare providers and employers when developing pandemic recovery plans.

Indexed as

COVID-19PandemicsAdolescentAdultCross-Sectional StudiesFemaleHumansMenstrual CycleRetrospective Studies

Identifiers

PMID37819943
PMCPMC10566721
OpenAlexW4387526335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.