Evidence map›Paper›PMID 37819899›Full record

ArticlePloS one2023

South Asian, Black and White ethnicity and the effect of potentially modifiable risk factors for dementia: A study in English electronic health records.

Naaheed Mukadam, Louise Marston, Gemma Lewis, Rohini Mathur, Ed Lowther, Greta Rait, Gill Livingston

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The landscape of dementia in India: Prevalence, risk factors, and opportunities ahead.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Article
  15. Sex differences in modifiable dementia risk factors: Findings from the Rush Memory and Aging Project.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  16. Estimating the impact of risk factor reduction on dementia prevalence in New Zealand.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Naaheed MukadamDivision of Psychiatry, University College London, London, United Kingdom.ORCID 0000-0001-8635-9521
Louise MarstonPrimary Care & Population Health, University College London, London, United Kingdom.ORCID 0000-0002-9973-1131
Gemma LewisDivision of Psychiatry, University College London, London, United Kingdom.
Rohini MathurWolfson Institute of Population Health, Queen Mary University London, London, United Kingdom.ORCID 0000-0002-3817-8790
Ed LowtherAdvanced Research Computing Centre, University College London, London, United Kingdom.ORCID 0009-0007-0556-5245
Greta RaitPrimary Care & Population Health, University College London, London, United Kingdom.
Gill LivingstonDivision of Psychiatry, University College London, London, United Kingdom.
University College London · GBQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to investigate ethnic differences in the associations of potentially modifiable risk factors with dementia.

methodsWe used anonymised data from English electronic primary care records for adults aged 65 and older between 1997 and 2018. We used Cox regression to investigate main effects for each risk factor and interaction effects between each risk factor and ethnicity.

resultsWe included 865,674 people with 8,479,973 person years of follow up. Hypertension, dyslipidaemia, obesity and diabetes were more common in people from minority ethnic groups than White people. The impact of hypertension, obesity, diabetes, low HDL and sleep disorders on dementia risk was increased in South Asian people compared to White people. The impact of hypertension was greater in Black compared to White people. DISCUSSION: Dementia prevention efforts should be targeted towards people from minority ethnic groups and tailored to risk factors of particular importance.

Indexed as

DementiaElectronic Health RecordsHypertensionAgedBlack or African AmericanDiabetes MellitusEthnicityHumansObesityRisk FactorsSouth Asian PeopleWhite People

Identifiers

PMID37819899
PMCPMC10566703
OpenAlexW4387517654

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.