Evidence map›Paper›PMID 37819407›Full record

ArticleLasers in medical science2023

Effects of low level laser on periodontal tissue remodeling in hPDLCs under tensile stress.

Jiaxi Zhang, Xizhong Zhang, Kaifang Han, Xuan Wang, Ziyuan Guo, Qi Deng, Jiahui Li, Shuxin Lv, Wenwen Yu

Open access · hybridAbstract read
In one paragraph

Article in Lasers in medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiaxi ZhangDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Xizhong ZhangDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Kaifang HanDepartment of Stomatology, Tianjin Beichen Hospital, Tianjin, 300400, China.
Xuan WangDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Ziyuan GuoDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Qi DengDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Jiahui LiDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Shuxin LvDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China.
Wenwen YuDepartment of Orthodontics, Tianjin Stomatological Hospital, School of Medicine, Nankai University, Tianjin, 300041, China. yuwenwen8802@163.com.
Tianjin Stomatological Hospital · CNTianjin Beichen Hospital · CNTianjin University · CN

Funding

Tianjin Health Technology Project No. ZC20001Tianjin's 13th Five Year Plan for the Construction of Clinical Key Disciplines (Jin Wei Ke Jiao [2018] No. 268) sub project No. ZDPY-13
6 · The paper itself

Abstract

This study aimed to investigate the effect of Low-Level Laser Therapy (LLLT) on human Periodontal Ligament Cells (hPDLCs) under tension stress. Primary hPDLCs were obtained using the tissue culture method, and P3 cells were utilized for the subsequent experiments. The study comprised four groups: a blank control group (Group B), a laser irradiation group (Group L), a tension stress group (Group T), and a laser + tension stress group (Group LT). Mechanical loading was applied using an in-vitro cell stress loading device at a frequency of 0.5 Hz and deformation of 2% for two hours per day for two days. Laser irradiation at 808 nm GaAlAs laser was administered 1 h after force loading. Cell samples were collected after the experiment. Bone and fiber remodeling factors were analyzed using PCR and Western blot. Flow cytometry was employed to assess the cell cycle, while ROS and Ca

Indexed as

OsteogenesisPeriodontal LigamentCell DifferentiationCells, CulturedHumansLasersReactive Oxygen SpeciesReactive Oxygen SpeciesCa2+LaserPeriodontal ligament cellsROSTension stressTissue remolding

Identifiers

PMID37819407
PMCPMC10567958
OpenAlexW4387537115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.