Evidence map›Paper›PMID 37819140›Full record

ArticlemSphere2023

Recyclable CRISPR/Cas9-mediated gene disruption and deletions in

Bastian Joehnk, Nebat Ali, Mark Voorhies, Keith Walcott, Anita Sil

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Tools for genetic manipulation of the endemic fungal pathogen,bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Genotypic diversity, virulence, and molecular genetic tools inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bastian JoehnkDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Nebat AliDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-9622-3393
Mark VoorhiesDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0001-8815-7384
Keith WalcottDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Anita SilDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-3987-7534
University of California, San Francisco · US

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAISSE, CHRISTIAN · 2003 to 2019
$21.8M
Tetrad: Genetics, Cell Biology, Biochemistry and Molecular Biology Training GrantT32GM139786 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Natalia Jura, David Paul Toczyski · 2021 to 2026
$6.5M
Gene circuits that control morphology in HistoplasmaR37AI066224 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Anita Sil · 2020 to 2026
$3.3M
NIAID NIH HHS R37 AI066224NIDDK NIH HHS P30 DK063720NIGMS NIH HHS T32 GM139786
6 · The paper itself

Abstract

importance

Indexed as

CRISPR-Cas SystemsHistoplasmaAnimalsHomologous RecombinationMammalsMutagenesis, InsertionalMutagenesis, Site-DirectedCRISPRfungal pathogenesisgenome editingHistoplasma

Identifiers

PMID37819140
PMCPMC10732100
OpenAlexW4387529447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.