Evidence map›Paper›PMID 37818942›Full record

Observational studyeLife2023

An observational treatment study of metacognition in anxious-depression.

Celine Ann Fox, Chi Tak Lee, Anna Kathleen Hanlon, Tricia X F Seow, Kevin Lynch, Siobhán Harty, Derek Richards, Jorge Palacios, Veronica O'Keane, Klaas Enno Stephan and 1 more

Abstract readObservational Study
In one paragraph

Observational study in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Towards an integrative neuroscience of metacognition.Nature reviews. Neuroscience · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Neural Correlates of Metacognition Impairment in Opioid Addiction.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Article
  11. Article
  12. Article
  13. Confidence biases in problem gambling.Journal of behavioral addictions · 2024
    Article
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Celine Ann FoxSchool of Psychology, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0003-1740-3765
Chi Tak LeeSchool of Psychology, Trinity College Dublin, Dublin, Ireland.
Anna Kathleen HanlonSchool of Psychology, Trinity College Dublin, Dublin, Ireland.
Tricia X F SeowWellcome Centre for Human Neuroimaging, University College London, London, United Kingdom.ORCID 0000-0002-5930-8929
Kevin LynchSchool of Psychology, Trinity College Dublin, Dublin, Ireland.
Siobhán HartySilverCloud Science, SilverCloud Health Ltd, Dublin, Ireland.
Derek RichardsSchool of Psychology, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0003-0871-4078
Jorge PalaciosSchool of Psychology, Trinity College Dublin, Dublin, Ireland.
Veronica O'KeaneDepartment of Psychiatry, Trinity College Dublin, Dublin, Ireland.
Klaas Enno StephanTranslational Neuroimaging Unit (TNU), Institute for Biomedical Engineering, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-8594-9092
Claire M GillanSchool of Psychology, Trinity College Dublin, Dublin, Ireland.ORCID 0000-0001-9065-403X

Funding

European Research Council ERC-H2020-HABITScience Foundation Ireland 19/FFP/6418
6 · The paper itself

Abstract

Prior studies have found metacognitive biases are linked to a transdiagnostic dimension of anxious-depression, manifesting as reduced confidence in performance. However, previous work has been cross-sectional and so it is unclear if under-confidence is a trait-like marker of anxious-depression vulnerability, or if it resolves when anxious-depression improves. Data were collected as part of a large-scale transdiagnostic, four-week observational study of individuals initiating internet-based cognitive behavioural therapy (iCBT) or antidepressant medication. Self-reported clinical questionnaires and perceptual task performance were gathered to assess anxious-depression and metacognitive bias at baseline and 4-week follow-up. Primary analyses were conducted for individuals who received iCBT (n=649), with comparisons between smaller samples that received antidepressant medication (n=82) and a control group receiving no intervention (n=88). Prior to receiving treatment, anxious-depression severity was associated with under-confidence in performance in the iCBT arm, replicating previous work. From baseline to follow-up, levels of anxious-depression were significantly reduced, and this was accompanied by a significant increase in metacognitive confidence in the iCBT arm (

Indexed as

DepressionMetacognitionAntidepressive AgentsAnxietyCross-Sectional StudiesHumansInternetTreatment OutcomeAntidepressive Agentsantidepressantanxious-depressionconfidencehumaniCBTmetacognitionneurosciencetransdiagnostic

Identifiers

PMID37818942
PMCPMC10567110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.