Evidence map›Paper›PMID 37818777›Full record

ArticlePediatric pulmonology2024

A personalized medicine approach to optimize care for a pediatric cystic fibrosis patient with atypical clinical symptoms.

Jesun Lee, Ammar Husami, Kavisha Arora, Weiqiang Zhang, Ferdous Kadri, Sunitha Yarlagadda, Changsuk Moon, Kyu Shik Mun, Kejian Zhang, Yunjie Huang and 6 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric pulmonology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jesun LeeDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.
Ammar HusamiDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0002-4287-2857
Kavisha AroraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.ORCID 0009-0003-9888-929X
Weiqiang ZhangUSDA-ARS, Pollinator Health in Southern Crop Ecosystem Research Unit, Stoneville, Mississippi, USA.
Ferdous KadriDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.
Sunitha YarlagaddaDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Changsuk MoonDecibel Therapeutics, Inc., Boston, Massachusetts, USA.
Kyu Shik MunDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.
Kejian ZhangDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Yunjie HuangIndiana University School of Medicine, Indianapolis, Indiana, USA.
Pramodha LiyanageDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.
John BrewingtonDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
John P ClancyCystic Fibrosis Foundation, Bethesda, Maryland, USA.
Ala ShaikhkhalilDepartments of Pulmonary and Gastrointestinal Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID 0000-0003-1812-8064
Grace PaulDepartments of Pulmonary and Gastrointestinal Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID 0000-0003-0963-1784
Anjaparavanda P NarenDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Hospital Medical Center, Los Angeles, California, USA.

Funding

Pilot and Feasibility ProgramP30DK117467 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Raouf S. Amin, MICHAEL A. HELMRATH · 2018 to 2026
$11.4M
Inhibition of an apical cAMP transporter (MRP4) in the gut induces diarrheaR01DK080834 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Anjaparavanda P Naren · 2009 to 2026
$6.8M
Investigating of the Mechanisms of Action of CFTR Correctors in RescuingDelta F508-CFTRR01HL147351 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI NAREN, ANJAPARAVANDA P · 2020 to 2023
$1.7M
NHLBI NIH HHS R01 HL147351NIDDK NIH HHS P30 DK117467NIDDK NIH HHS R01 DK080834NIH HHS DK080834NIH HHS HL147351NIH HHS P30-DK117467
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cystic FibrosisChildCystic Fibrosis Transmembrane Conductance RegulatorHumansMutationPrecision MedicineCystic Fibrosis Transmembrane Conductance Regulator

Identifiers

PMID37818777
PMCPMC10842517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.