Evidence map›Paper›PMID 37818569›Full record

ReviewCurrent drug delivery2024

Research Progress on Immunomodulatory Effects of Poly (Lactic-co- Glycolic Acid) Nanoparticles Loaded with Traditional Chinese Medicine Monomers.

Bocui Song, Qian Chen, Chunyu Tong, Yuqi Li, Shuang Li, Xue Shen, Wenqi Niu, Meihan Hao, Yunfei Ma, Yanhong Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bocui SongDepartment of Pharmaceutical Engineering, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.ORCID 0000-0003-3532-2950
Qian ChenCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.ORCID 0000-0002-5791-5063
Chunyu TongDepartment of Biological Science, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.ORCID 0000-0003-4495-5864
Yuqi LiCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.ORCID 0000-0002-5608-6718
Shuang LiCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.ORCID 0009-0007-4913-8923
Xue ShenCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.
Wenqi NiuCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.
Meihan HaoCollege of Life Science & Technology, Heilongjiang Bayi Agricultura University, Daqing 163319, China.
Yunfei MaDepartment of Pharmaceutical Engineering, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Yanhong WangDepartment of Biological Engineering, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.ORCID 0000-0002-3651-0091
Heilongjiang Bayi Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunomodulatory mechanisms are indispensable and key factors in maintaining the balance of the environment in humans. When the immune function of the immune system is impaired, autoimmune diseases occur. Excessive body fatigue, natural aging of the human body, malnutrition, genetic factors and other reasons cause low immune function, due to which the body is prone to being infected by bacteria or cancer. Clinically, the existing therapeutic drugs still have problems such as high toxicity, long treatment cycle, drug resistance and high price, so we still need to explore and develop a high efficiency and low toxicity drug. Poly(lactic-co-glycolic acid) (PLGA) refers to a nontoxic polymer compound that exhibits excellent biocompatibility. Traditional Chinese medicine (TCM) monomers come from natural plants, and have the characteristics of high efficiency and low toxicity. Applying PLGA to TCM monomers can make up for the defects of traditional dosage forms, improve bioavailability, reduce the frequency and dosage of drug use, and reduce toxicity and side effects, thus having the characteristics of sustained release and targeting. Accordingly, PLGA nanoparticles loaded with TCM monomers have been the focus of development. The previous research on drug loading advantages, preparation methods, and immune regulation of TCM PLGA nanoparticles is summarized in the following sections.

Indexed as

Medicine, Chinese TraditionalNanoparticlesPolylactic Acid-Polyglycolic Acid CopolymerAnimalsDrug CarriersDrugs, Chinese HerbalHumansImmunologic FactorsImmunomodulating AgentsDrug CarriersDrugs, Chinese HerbalImmunologic FactorsImmunomodulating AgentsPolylactic Acid-Polyglycolic Acid Copolymerbioavailabilitydrug deliveryimmunizationnanoparticlesPoly (lactic-co-glycolic acid)traditional Chinese medicine monomers.

Identifiers

PMID37818569
OpenAlexW4387515841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.