Evidence map›Paper›PMID 37818565›Full record

ArticleCurrent radiopharmaceuticals2024

Radiolabeling of Zonisamide for a Diagnostic Perspective.

Emine Dervis, Kadriye Busra Karatay, Kubra Durkan, Ayfer Yurt Kilcar

Abstract read
PubMed Publisher
In one paragraph

Article in Current radiopharmaceuticals, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emine DervisDepartment of Nuclear Applications, Institute of Nuclear Sciences, Ege University, Izmir, Turkey.ORCID 0000-0002-0205-2790
Kadriye Busra KaratayDepartment of Nuclear Applications, Institute of Nuclear Sciences, Ege University, Izmir, Turkey.ORCID 0000-0002-2811-4689
Kubra DurkanDepartment of Nuclear Applications, Institute of Nuclear Sciences, Ege University, Izmir, Turkey.ORCID 0000-0002-0783-8557
Ayfer Yurt KilcarDepartment of Nuclear Applications, Institute of Nuclear Sciences, Ege University, Izmir, Turkey.ORCID 0000-0003-0866-7515
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEpilepsy is one of the oldest and the most common chronic neurological diseases. Antiepileptic drugs (AEDs) are the backbone of epilepsy treatment. However, epileptogenesis has not been fully elucidated. One of the critical reasons for this is the lack of reliable biomarkers. Neuroimaging suggests a non-invasive examination and investigation tool that can detect critical pathophysiological changes involved in epileptogenesis and monitor disease progression. In the current study, the radiolabeling potential of Zonisamide (ZNS) (the secondgeneration AED) with Technetium-

methodsZNS was labeled with

resultsThe radiochemical yield of [

conclusionThis study showed that the current radiolabeled antiepileptic drug has a diagnostic potential to be used in imaging neurological processes.

Indexed as

AnticonvulsantsRadiopharmaceuticalsZonisamideCell Line, TumorEpilepsyHumansIsotope LabelingIsoxazolesOrganotechnetium CompoundsTechnetiumAnticonvulsantsIsoxazolesOrganotechnetium CompoundsRadiopharmaceuticalsTechnetiumZonisamideantiepileptic drugsepilepsyin vitro.neuroimagingtechnetium-99m (99mTc)Zonisamide (ZNS)

Identifiers

PMID37818565
OpenAlexW4387516106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.