ArticlePeerJ2023
Neural drive and motor unit characteristics after anterior cruciate ligament reconstruction: implications for quadriceps weakness.
Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Changes in Quadriceps Force Control and Torque Quality Following Anterior Cruciate Ligament Injury and Reconstruction: Associations with Functional Performance-A Systematic Review and Meta-Analysis.Sports medicine - open · 2026Pooled it
- Early sub-maximal quadriceps motor unit firing characteristics and six-month knee extensor strength after anterior cruciate ligament reconstruction: a prospective longitudinal study.Annals of medicine · 2026Article
- Sex-Specific Analysis of Quadriceps and Hamstring Strength Following Anterior Cruciate Ligament Reconstruction With or Without Meniscal Repair.Journal of functional morphology and kinesiology · 2026Article
- [Emerging role of brain-computer interface in orthopedic rehabilitation and motor function restoration].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Auditory-cued terminal knee extension enhances vastus medialis motor unit function in the early phase following ACL reconstruction: a randomized controlled trial.Knee surgery & related research · 2026Article
- Joint effusion after anterior cruciate ligament reconstruction: Associations with higher postoperative physical activity, patella alta and increased quadriceps tension.Journal of experimental orthopaedics · 2026Article
- Strength development following a six-week risk reduction athletic development training program in men and women.Sports medicine and health science · 2025Article
- fMRI Activation in Sensorimotor Regions at 6 Weeks After Anterior Cruciate Ligament Reconstruction.The American journal of sports medicine · 2025Article
- Knee muscle strength and steadiness for individuals with anterior cruciate ligament reconstruction and knee osteoarthritis.Clinical biomechanics (Bristol, Avon) · 2024Article
- Quadriceps Activation After Anterior Cruciate Ligament Reconstruction: The Early Bird Gets the Worm!International journal of sports physical therapy · 2024Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The purpose of this investigation was to compare the quality of neural drive and recruited quadriceps motor units' (MU) action potential amplitude (MUAP Methods: Fourteen individuals with ACLR and 13 matched controls performed trapezoidal knee extensor contractions at 30%, 50%, 70%, and 100% of their maximal voluntary isometric contraction (MVIC). Decomposition electromyography (dEMG) and torque were recorded concurrently. The Hoffmann reflex (H-reflex) and central activation ratio (CAR) were acquired bilaterally to detail the proportion of MU pool available and volitionally activated. We examined MUAP Results: Individuals with ACLR demonstrated lower MVIC torque in the involved limb compared to uninvolved limb. There were no differences in H-reflex or CAR between groups or limbs. The ACLR involved limb demonstrated smaller mass-normalized RT range and slower MU firing rates at high contraction intensities (70% and 100% MVIC) compared to uninvolved and control limbs. The ACLR involved limb also demonstrated larger MU action potentials in the VM compared to the contralateral limb. These differences were largely attenuated with relative RT normalization. Conclusions: These results suggest that persistent strength deficits following ACLR may be attributable to a diminished quadriceps motor neuron pool and inability to upregulate the firing rate of recruited MUs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.