Evidence map›Paper›PMID 37818232›Full record

ArticleResearch and reports in urology2023

Epithelioid Angiomyolipoma with Tumor Thrombus into Inferior Vena Cava Presurgically Treated with Combination Therapy of Pembrolizumab and Axitinib: A Case Report.

Chihiro Kawasoe, Yoshi Miyamoto, Kaoru Ito, Takaya Murashima, Takahiro Nagai, Hiroki Takamori, Takumi Kiwaki, Toshio Kamimura, Shoichiro Mukai, Toshiyuki Kamoto

Open access · goldAbstract readCase Reports
In one paragraph

Article in Research and reports in urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chihiro KawasoeDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Yoshi MiyamotoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Kaoru ItoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Takaya MurashimaDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Takahiro NagaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.ORCID 0000-0001-8427-644X
Hiroki TakamoriDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Takumi KiwakiSection of Oncopathology and Regenerative Biology, Faculty of Medicine, Miyazaki University, Miyazaki, Japan.ORCID 0000-0002-6931-8055
Toshio KamimuraDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Shoichiro MukaiDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
Toshiyuki KamotoDepartment of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan.
University of Miyazaki Hospital · JPKoga Hospital · JPMiyazaki Prefectural Hospital · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelioid angiomyolipoma (EAML) is a rare variant of AML with malignant potential. It is occasionally difficult to distinguish EAML from renal cell carcinoma (RCC) on imaging. A 72-year-old woman was admitted to our hospital for the treatment of a left renal tumor with relatively high blood flow and a tumor thrombus extending to the inferior vena cava, suggesting RCC. The patient underwent presurgical combination therapy with axitinib and pembrolizumab. This treatment significantly shortened the thrombus, and radical nephrectomy was performed. The pathological findings were compatible with EAML, and the treatment effects were observed. We report a case treated pre-surgically with a combined therapy of pembrolizumab and axitinib, with a favorable response as a treatment option for EAML.

Indexed as

axitinibepithelioid angiomyolipomapembrolizumabpresurgical treatmenttumor thrombus

Identifiers

PMID37818232
PMCPMC10561617
OpenAlexW4387370823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.